anti-Monkey Aurora Kinase B antibody for Enzyme Immunoassay

Recommended Aurora Kinase B Antibody

Antigen
Aurora Kinase B (AURKB) Antibodies
  • AIK2
  • AIM-1
  • AIM1
  • ARK2
  • AurB
  • IPL1
  • PPP1R48
  • STK12
  • STK5
  • aurkb-sv1
  • aurkb-sv2
  • AIRK2
  • AL022959
  • Aik2
  • Aim1
  • Ark2
  • STK-1
  • Stk12
  • Stk5
  • Aur B
  • Aurora B
  • Aurora-B
  • CG6620
  • DmAIRK2
  • DmAurB
  • DmAuroraB
  • Dmel\\CG6620
  • IAL
  • IAL1
  • Ial
  • aurB
  • aurora B
  • ARK-2
  • XAIRK2
  • aik2
  • aim-1
  • aim1
  • airk2
  • ark2
  • ipl1
  • stk12
  • stk5
  • CHUNP6896
  • fa09g06
  • stka
  • wu:fa09g06
  • aurkb
  • AIRK2-B
  • XAIRK2-B
  • aurkb-a
  • aurkb-b
  • xAurora-B-B
  • aurora kinase B
  • aurora B
  • aurora kinase B S homeolog
  • AURKB
  • Aurkb
  • aurB
  • aurkb
  • aurkb.S
Epitope
AA 227-238
32
32
28
21
16
12
12
10
10
9
7
7
7
7
6
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rat (Rattus)
279
119
91
16
7
6
3
2
2
2
1
1
1
Host
Rabbit
215
60
7
7
Clonality
Polyclonal
Conjugate
This Aurora Kinase B antibody is un-conjugated
12
9
9
8
8
7
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
229
143
97
93
43
32
15
12
11
9
8
2
2
1
Options
Catalog No. ABIN318827
$ 478.50
Plus shipping costs $45.00

General

Antigen Aurora Kinase B (AURKB) Antibodies
Epitope AA 227-238
(32), (32), (28), (21), (16), (12), (12), (10), (10), (9), (7), (7), (7), (7), (6), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(279), (119), (91), (16), (7), (6), (3), (2), (2), (2), (1), (1), (1)
Host Rabbit
(215), (60), (7), (7)
Clonality
Polyclonal
Conjugate This Aurora Kinase B antibody is un-conjugated
(12), (9), (9), (8), (8), (7), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(229), (143), (97), (93), (43), (32), (15), (12), (11), (9), (8), (2), (2), (1)
Pubmed 2 references available
Supplier

Product Details anti-Aurora Kinase B Antibody

Target Details Aurora Kinase B Application Details Handling References for anti-Aurora Kinase B antibody (ABIN318827) Images
Specificity This antibody detects Aurora-B kinase (AurB).
Cross-Reactivity (Details) Species reactivity (expected):Rat, Bovine, Mouse, Chimpanzee, Dog, Pig.
Species reactivity (tested):Human.
Purification Affinity Chromatography
Immunogen Synthetic peptide corresponding to amino acids 227-238 of human Aurora-B kinase.
Isotype IgG
Plasmids, Primers & others

Target Details Aurora Kinase B

Product Details anti-Aurora Kinase B Antibody Application Details Handling References for anti-Aurora Kinase B antibody (ABIN318827) Images back to top
Antigen
Alternative Name Aurora Kinase B (AURKB Antibody Abstract)
Background Aurora-B kinase is a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC). This complex functions in chromosome alignment and separation, histone modification, and cytokinesis. CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localisation, stability, and possibly even the substrate specificity of AurB. Two CPCs exist during mitosis- one containing all four members, and another consisting of INCENP and AurB. Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3. AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples. Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.Synonyms: AIK2, AIM1, ARK2, AURKB, Aurora- and Ipl1-like midbody-associated protein 1, Aurora-B, Aurora/IPL1-related kinase 2, STK-1, STK12, Serine/threonine-protein kinase 12
Gene ID 9212
NCBI Accession NP_004208
UniProt Q96GD4
Pathways TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-Aurora Kinase B Antibody Target Details Aurora Kinase B Handling References for anti-Aurora Kinase B antibody (ABIN318827) Images back to top
Application Notes ELISA: 1: 2000 - 1: 10000. Western Blot: 1: 250 - 1: 1000, detects a band of approximately 39 kDa in HeLa cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Aurora Kinase B Antibody Target Details Aurora Kinase B Application Details References for anti-Aurora Kinase B antibody (ABIN318827) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate buffered saline pH 7.2 containing 0.09 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Aurora Kinase B antibody (ABIN318827)

Product Details anti-Aurora Kinase B Antibody Target Details Aurora Kinase B Application Details Handling Images back to top
Background publications

Vader, Medema, Lens: "The chromosomal passenger complex: guiding Aurora-B through mitosis." in: The Journal of cell biology, Vol. 173, Issue 6, pp. 833-7, 2006

Keen, Taylor: "Aurora-kinase inhibitors as anticancer agents." in: Nature reviews. Cancer, Vol. 4, Issue 12, pp. 927-36, 2004