anti-Rat (Rattus) Aurora Kinase B antibody for ELISA

Recommended Aurora Kinase B Antibody

Antigen
Aurora Kinase B (AURKB) Antibodies
  • AIK2
  • AIM-1
  • AIM1
  • ARK2
  • AurB
  • IPL1
  • PPP1R48
  • STK12
  • STK5
  • aurkb-sv1
  • aurkb-sv2
  • AIRK2
  • AL022959
  • Aik2
  • Aim1
  • Ark2
  • STK-1
  • Stk12
  • Stk5
  • Aur B
  • Aurora B
  • Aurora-B
  • CG6620
  • DmAIRK2
  • DmAurB
  • DmAuroraB
  • Dmel\\CG6620
  • IAL
  • IAL1
  • Ial
  • aurB
  • aurora B
  • ARK-2
  • XAIRK2
  • aik2
  • aim-1
  • aim1
  • airk2
  • ark2
  • ipl1
  • stk12
  • stk5
  • CHUNP6896
  • fa09g06
  • stka
  • wu:fa09g06
  • aurkb
  • AIRK2-B
  • XAIRK2-B
  • aurkb-a
  • aurkb-b
  • xAurora-B-B
  • aurora kinase B
  • aurora B
  • aurora kinase B S homeolog
  • AURKB
  • Aurkb
  • aurB
  • aurkb
  • aurkb.S
Epitope
AA 6-35
32
32
28
21
16
13
12
10
10
8
7
7
7
7
6
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Primate, Rat (Rattus)
279
119
91
17
8
7
4
2
2
1
1
1
1
Host
Rabbit
215
60
7
7
Clonality
Polyclonal
Conjugate
This Aurora Kinase B antibody is un-conjugated
12
9
9
8
8
7
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
229
142
96
93
43
32
15
12
11
10
8
2
2
1
Options

Available images

Catalog No. ABIN3030076
$ 452.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
16.551027 ABIN3183366 ELISA IF IHC WB Rabbit IgG Tyr436 Polyclonal 0
16.551027 ABIN3183367 ELISA IF IHC WB Rabbit IgG Tyr434, Tyr437 Polyclonal 0
13.551027 ABIN3182642 ELISA IHC WB Rabbit IgG pTyr12 Polyclonal 0
13.551027 ABIN3182806 ELISA IF IHC WB Rabbit IgG pThr232 Polyclonal 0
13 ABIN6256516 ELISA ICC IF IHC WB Rabbit IgG pThr232 Polyclonal 0
13 ABIN6260155 ELISA ICC IF WB Rabbit IgG Polyclonal 0
10 ABIN1531642 IF IHC ELISA WB Rabbit IgG AA 198-247, pThr232 Polyclonal 0
10 ABIN1532733 IF IHC ELISA WB Rabbit IgG AA 1-50 Polyclonal 0
10 ABIN6260154 ELISA ICC IF IHC WB Rabbit IgG Polyclonal 0
10 ABIN1574917 IF IHC ELISA WB Rabbit IgG pThr232 Polyclonal 0
10 ABIN1574919 IF IHC ELISA WB Rabbit IgG Polyclonal 0
7 ABIN1531706 IHC ELISA WB Rabbit IgG AA 1-50, pTyr12 Polyclonal 0
7 ABIN1532664 IF ELISA WB Rabbit IgG AA 198-247 Polyclonal 0
7 ABIN1574918 IHC ELISA WB Rabbit IgG pTyr12 Polyclonal 0
5.5 ABIN2477557 ELISA WB Rabbit IgG AA 227-238 Polyclonal 2
4 ABIN2878837 ELISA IF IHC IHC (p) WB Rabbit IgG AA 1-50 Polyclonal 0
4 ABIN2878787 ELISA IF IHC IHC (p) WB Rabbit IgG AA 198-247 Polyclonal 0
4 ABIN5955801 ELISA IF IHC (p) WB Rabbit IgG Tyr12 Polyclonal 0
4 ABIN331287 IP ELISA WB Mouse IgG2a, kappa 0
4 ABIN1732116 IF IHC (p) ELISA WB Rabbit IgG Internal Region Polyclonal 0

General

Antigen Aurora Kinase B (AURKB) Antibodies
Epitope AA 6-35
(32), (32), (28), (21), (16), (13), (12), (10), (10), (8), (7), (7), (7), (7), (6), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Primate, Rat (Rattus)
(279), (119), (91), (17), (8), (7), (4), (2), (2), (1), (1), (1), (1)
Host Rabbit
(215), (60), (7), (7)
Clonality
Polyclonal
Conjugate This Aurora Kinase B antibody is un-conjugated
(12), (9), (9), (8), (8), (7), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(229), (142), (96), (93), (43), (32), (15), (12), (11), (10), (8), (2), (2), (1)
Supplier

Product Details anti-Aurora Kinase B Antibody

Target Details Aurora Kinase B Application Details Handling Images
Purification Purified
Immunogen A portion of amino acids 6-35 from the human protein was used as the immunogen for this Aurora B antibody.
Isotype Ig Fraction
Plasmids, Primers & others

Target Details Aurora Kinase B

Product Details anti-Aurora Kinase B Antibody Application Details Handling Images back to top
Antigen
Alternative Name Aurora B (AURKB Antibody Abstract)
Background Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes: acts by mediating phosphorylation of H3S28ph at active promoters in resting B-cells, inhibiting RNF2/RING1B-mediated ubiquitination of histone H2A and enhancing binding and activity of the USP16 deubiquitinase at transcribed genes. [UniProt]
UniProt Q96GD4
Pathways TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-Aurora Kinase B Antibody Target Details Aurora Kinase B Handling Images back to top
Application Notes Titration of the Aurora B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Restrictions For Research Use only

Handling

Product Details anti-Aurora Kinase B Antibody Target Details Aurora Kinase B Application Details Images back to top
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the Aurora B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Images

Product Details anti-Aurora Kinase B Antibody Target Details Aurora Kinase B Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Aurora Kinase B (AURKB) (AA 6-35) antibody (ABIN3030076) IHC analysis of FFPE human testis tissue stained with Aurora B antibody
Western Blotting (WB) image for anti-Aurora Kinase B (AURKB) (AA 6-35) antibody (ABIN3030076) Western blot analysis of Aurora B antibody and 293 cell lysate (2 ug/lane) either non...
Western Blotting (WB) image for anti-Aurora Kinase B (AURKB) (AA 6-35) antibody (ABIN3030076) Western blot analysis of Aurora B antibody and HepG2 lysate. Predicted molecular weig...
Western Blotting (WB) image for anti-Aurora Kinase B (AURKB) (AA 6-35) antibody (ABIN3030076) Western blot analysis of Aurora B antibody and HepG2 lysate. Predicted molecular weig...
Immunohistochemistry (IHC) image for anti-Aurora Kinase B (AURKB) (AA 6-35) antibody (ABIN3030076) IHC analysis of FFPE human testis tissue stained with Aurora B antibody
Immunohistochemistry (IHC) image for anti-Aurora Kinase B (AURKB) (AA 6-35) antibody (ABIN3030076) IHC analysis of FFPE human hepatocarcinoma tissue stained with the Aurora B antibody