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anti-Human BCL10 Antibodies:
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Human Monoclonal BCL10 Primary Antibody for IHC (p), IHC - ABIN269575
Ye, Dogan, Karran, Willis, Chen, Wlodarska, Dyer, Isaacson, Du: BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma. in The American journal of pathology 2000
Show all 5 Pubmed References
Human Monoclonal BCL10 Primary Antibody for WB - ABIN1944800
Koseki, Inohara, Chen, Carrio, Merino, Hottiger, Nabel, Núñez: CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10. in The Journal of biological chemistry 1999
Show all 4 Pubmed References
Human Monoclonal BCL10 Primary Antibody for ICC, FACS - ABIN1724629
Willis, Jadayel, Du, Peng, Perry, Abdul-Rauf, Price, Karran, Majekodunmi, Wlodarska, Pan, Crook, Hamoudi, Isaacson, Dyer: Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. in Cell 1999
Show all 3 Pubmed References
Human Monoclonal BCL10 Primary Antibody for IHC, ELISA - ABIN965650
Lucas, Yonezumi, Inohara, McAllister-Lucas, Abazeed, Chen, Yamaoka, Seto, Nunez: Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. in The Journal of biological chemistry 2001
Show all 7 Pubmed References
Human Polyclonal BCL10 Primary Antibody for WB - ABIN153020
Nagy, Rui, Stepkowski, Karras, Kirken: A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Monoclonal BCL10 Primary Antibody for CyTOF, ELISA - ABIN4283294
Bhattacharyya, Pant, Dudeja, Tobacman: Development, evaluation, and application of a highly sensitive microtiter plate ELISA for human Bcl10 protein. in Journal of immunoassay & immunochemistry 2007
Human Monoclonal BCL10 Primary Antibody for FACS, IHC (p) - ABIN2477593
Sirchia, Lewis: Paroxysmal nocturnal haemoglobinuria. in Clinics in haematology 1976
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Human Monoclonal BCL10 Primary Antibody for FACS - ABIN2477594
Ye, Gong, Liu, Hamoudi, Shirali, Ho, Chott, Streubel, Siebert, Gesk, Martin-Subero, Radford, Banerjee, Nicholson, Ranaldi, Remstein, Gao, Zheng, Isaacson, Dogan, Du: MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression. in The Journal of pathology 2005
Show all 2 Pubmed References
results define molecular determinants that control the production of Lin(Ub)n-Bcl10, an important signaling intermediate in TCR and oncogenic CARD11 (show CARD11 Antibodies) signaling.
Psoriasis mutations disrupt CARD14 (show CARD14 Antibodies) autoinhibition promoting BCL10-MALT1 (show MALT1 Antibodies)-dependent NF-kappaB (show NFKB1 Antibodies) activation
BCL10 promoted DNA double-strand breaks repair, enhancing cell survival after DNA damage.
Data show that caspase recruitment domain-containing protein 11 (show CARD11 Antibodies)/B-cell CLL/lymphoma 10/mucosa-associated lymphoid tissue lymphoma translocation gene 1 (show MALT1 Antibodies) signaling drives lymphoproliferation (show FAS Antibodies) through NF-kappa B (show NFKB1 Antibodies) and c-Jun N-terminal kinase activation.
BCL10 is not essential for actin polymerization after fibroblast FcgammaR stimulation.
characterization of zebrafish (Danio rerio) Bcl10
we identified BCL10 as a bona fide target of BCR (show BCR Antibodies)-induced linear ubiquitylation and demonstrated an important role of the linear ubiquitin ligase HOIP (show RNF31 Antibodies) in BCR (show BCR Antibodies)-induced phosphorylation
The results of this study indicate that inherited BCL10 deficiency should be considered in patients with combined immunodeficiency with B cell, T cell, and fibroblast defects.
B-cell lymphoma/leukemia 10 promotes oral cancer progression through STAT1 (show STAT1 Antibodies)/ATF4 (show ATF4 Antibodies)/S100P (show S100P Antibodies) signaling pathway.
BCL10 induces cleavage of MALT1 (show MALT1 Antibodies) at R149 in 293T cells.
Data show that BCL10 was located in cytoplasm in Pig Kidney Epithelial (PK15) cells.
Data found that, BCL10 expressed in high level in swine spleen, and with a modest level in thymus, brain and lymph node; low level mRNA was expressed in liver and not detectable level in kidney.
high fat diet (HFD) and zinc deficiency synergistically induce obesity-related cardiac hypertrophy (ORCH), by increasing oxidative stress-mediated activation of BCL10/CARD9 (show CARD9 Antibodies)/p38 MAPK (show MAPK14 Antibodies) signalling. Zinc supplement ameliorates ORCH through activation of metallothionein (show MT Antibodies) to repress oxidative stress-activated BCL10 expression and p38 MAPK (show MAPK14 Antibodies) activation.
Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity.
cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10.
Trehalose 6,6'-dimycolate-induced Mincle (show CLEC4E Antibodies) expression is dependent on Dectin-3-mediated NF-kappaB (show NFKB1 Antibodies) activation through the CARD9 (show CARD9 Antibodies)-BCL10-MALT1 (show MALT1 Antibodies) complex.
Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.
TCR-stimulated activation of NF-kappaB requires the assembly of cytosolic p62-Bcl10-Malt1-IKK signalosomes, which may ensure highly regulated activation of NF-kappaB in response to TCR engagement.
Bcl10 is an essential regulator for A20 (show TNFAIP3 Antibodies) gene expression.
Data indicate that caspase recruitment domain-containing protein 11 (CARD11 (show CARD11 Antibodies)) is involved in the pathogenesis of collagen-induced arthritis (CIA (show NCOA5 Antibodies)) by formation of the CARD11 (show CARD11 Antibodies)/Bcl10 complex and enhancement of the Th17 cell response.
Findings demonstrate a Bcl10 requirement for maximum development of carrageenan-induced inflammation and lack of complete suppression by IL-10 (show IL10 Antibodies) of carrageenan-induced inflammation.
Bcl10 links saturated fat overnutrition with hepatocellular NF-kB activation and insulin (show INS Antibodies) resistance.
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
B-cell lymphoma/leukemia 10
, CARD containing molecule enhancing NF-kB
, CARD-containing apoptotic signaling protein
, CARD-containing molecule enhancing NF-kappa-B
, CARD-containing proapoptotic protein
, CED-3/ICH-1 prodomain homologous E10-like regulator
, caspase-recruiting domain-containing protein
, cellular homolog of vCARMEN
, mammalian CARD-containing adapter molecule E10
, B-cell leukemia/lymphoma 10
, B-cell lymophoma 10 protein
, B-cell CLL/lymphoma 10
, B cell lymphoma/leukemia 10
, CARD-like apoptotic protein