We are preparing the requested document. Please wait, this may take a while...!
|Antigen||CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E) Antibodies|
|Conjugate||This CD3E antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro))
|9 references available|
|Supplier||Log in to see|
Product Details anti-CD3E AntibodyTarget Details CD3E Application Details Handling References for anti-CD3E antibody (ABIN3043629) Images
|Purpose||Mouse IgG monoclonal antibody for CD3, CD3e molecule, epsilon (CD3-TCR complex) (CD3E ) detection. Tested with IHC-F in Human. No cross reactivity with other proteins.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Mouse IgG monoclonal antibody for CD3, CD3e molecule, epsilon (CD3-TCR complex) (CD3E ) detection. Tested with IHC-F in Human.
Gene Name: CD3e molecule, epsilon(CD3-TCR complex)
Protein Name: T-cell surface glycoprotein CD3 epsilon chain
|Immunogen||Human thymocytes followed by Sezary T cells.|
Target Details CD3EProduct Details anti-CD3E Antibody Application Details Handling References for anti-CD3E antibody (ABIN3043629) Images back to top
|Alternative Name||CD3E (CD3E Antibody Abstract)|
The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3(formerly T3). Human CD3 consists of at least 4 proteins: gamma, delta, epsilon, and zeta. The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development.
Synonyms: T3E|T-cell surface antigen T3/Leu-4 epsilon chain
|Gene ID||916, 12501, 315609|
|UniProt||P07766, P22646, D4A5M2|
|Pathways||TCR Signaling, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-CD3E Antibody Target Details CD3E Handling References for anti-CD3E antibody (ABIN3043629) Images back to top
IHC-F: Concentration: 1 μg/mL, Species: Human
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by ABIN921230 in IHC(F).
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD3E Antibody Target Details CD3E Application Details References for anti-CD3E antibody (ABIN3043629) Images back to top
|Reconstitution||Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.|
|Buffer||Mouse ascites fluid, 1.2 % sodium acetate, 2 mg BSA, with 0.01 mg Sodium azide as preservative.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-CD3E antibody (ABIN3043629)Product Details anti-CD3E Antibody Target Details CD3E Application Details Handling Images back to top
|Product cited in:||
Chen, Liu, Xu, Yang, Zhang, Zhang: "Effectiveness of immune therapy combined with chemotherapy on the immune function and recurrence rate of cervical cancer." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 1063-1067, 2015
Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, 2013
Zhang, Zhou, Li, Wang, Tang, Chen, Lv, Zhao, Xing, Yu, Yu: "C-reactive protein/oxidised low-density lipoprotein/?2-glycoprotein I complex promotes atherosclerosis in diabetic BALB/c mice via p38mitogen-activated protein kinase signal pathway." in: Lipids in health and disease, Vol. 12, pp. 42, 2013
Yu, Li, Li, Zang, Liu: "TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice." in: Biological trace element research, Vol. 143, Issue 2, pp. 1064-76, 2011
Li, Geng, Du, Chen, Yang, Wu, Li, Schmidt, Przybylski: "Restricted TRBV repertoire in CD4+ and CD8+ T-cell subsets from CML patients." in: Hematology (Amsterdam, Netherlands), Vol. 16, Issue 1, pp. 43-9, 2011
Jia, Wang, Tong, Liu, Li, Zhang, Sun: "Biocompatibility of acellular nerves of different mammalian species for nerve tissue engineering." in: Artificial cells, blood substitutes, and immobilization biotechnology, Vol. 39, Issue 6, pp. 366-75, 2011
Liu, Cao, Ye, Wang, Song, Wang, Wang, Li, Deng: "Immunomodulatory effects of proanthocyanidin A-1 derived in vitro from Rhododendron spiciferum." in: Fitoterapia, Vol. 81, Issue 2, pp. 108-14, 2010
Li, Geng, Yin, Chen, Yang, Wu, Li, Du, Schmidt, Przybylski: "Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients." in: Journal of translational medicine, Vol. 8, pp. 47, 2010
Xie, Jia, He, Gao: "Morphological observation of tumor infiltrating immunocytes in human rectal cancer." in: World journal of gastroenterology, Vol. 12, Issue 11, pp. 1757-60, 2006