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|Antigen||CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E) Antibodies|
|Reactivity||Cow (Bovine), Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Orang-Utan (Pongo abelii), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine) Alternatives|
|Conjugate||This CD3E antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-CD3E AntibodyTarget Details CD3E Application Details Handling Images
|Purification||Protein A purified|
Amino acids ERPPPVPNPDYEP (156-168). Percent identity by BLAST analysis: Human, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Rabbit, Pig (100%), Chimpanzee, Gorilla, Ferret, Cat, Chicken, Dog (92%).
Type of Immunogen: Synthetic peptide
Target Details CD3EProduct Details anti-CD3E Antibody Application Details Handling Images back to top
|Alternative Name||CD3E (CD3E Antibody Abstract)|
Name/Gene ID: CD3E
Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon
|Pathways||TCR Signaling, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-CD3E Antibody Target Details CD3E Handling Images back to top
Approved: Flo (0.5 - 1 μg/10 x106), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD3E Antibody Target Details CD3E Application Details Images back to top
|Buffer||PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store at 2-8°C.|