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|Antigen||CD4 Molecule (CD4) Antibodies|
|Conjugate||This CD4 antibody is un-conjugated Alternatives|
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
|1 reference available|
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Product Details anti-CD4 AntibodyTarget Details CD4 Application Details Handling References for anti-CD4 antibody (ABIN371333) Images
|Characteristics||Synonyms: T4/Leu-3, T cell surface glycoprotein CD4, T Cell Surface Antigen T4/Leu3|
Target Details CD4Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 antibody (ABIN371333) Images back to top
|Alternative Name||CD4 (CD4 Antibody Abstract)|
|Background||CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4|
|Research Area||Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells|
|Pathways||TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 antibody (ABIN371333) Images back to top
Flow Cytometry. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). (Ref.2)Immunoprecipitation. Inhibition of mitogen-induced proliferation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 antibody (ABIN371333) Images back to top
|Buffer||100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-CD4 antibody (ABIN371333)Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Chan, Chen, Ager, Cooper: "Identification of the avian homologues of mammalian CD4 and CD8 antigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 140, Issue 7, pp. 2133-8, 1988