anti-Chimpanzee CD4 antibody for Blocking Reagent

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • L3T4
  • Ly-4
  • CD4mut
  • W3/25
  • p55
  • CD4 molecule
  • CD4 antigen
  • T-cell surface glycoprotein CD4
  • Cd4 molecule
  • CD4
  • cd4
  • Cd4
Reactivity
Chimpanzee, Human
1250
656
235
78
68
41
36
28
27
26
22
21
19
16
15
15
13
10
10
9
7
6
5
5
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
Host
Mammalian Cells
1422
611
283
16
6
1
1
Antibody Type
Recombinant Antibody
Clonality
Monoclonal
Conjugate
This CD4 antibody is un-conjugated
264
232
170
108
54
54
54
48
36
34
34
33
30
26
22
21
21
20
19
19
18
18
18
18
16
15
15
13
13
9
9
8
8
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Surface Plasmon Resonance (SPR)
1822
494
453
353
322
311
161
156
98
78
41
39
38
30
29
25
18
14
14
11
9
9
6
6
5
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
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Catalog No. ABIN5526280
$ 595.00
Plus shipping costs $45.00

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Chimpanzee, Human
(1250), (656), (235), (78), (68), (41), (36), (28), (27), (26), (22), (21), (19), (16), (15), (15), (13), (10), (10), (9), (7), (6), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mammalian Cells
(1422), (611), (283), (16), (6), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is un-conjugated
(264), (232), (170), (108), (54), (54), (54), (48), (36), (34), (34), (33), (30), (26), (22), (21), (21), (20), (19), (19), (18), (18), (18), (18), (16), (15), (15), (13), (13), (9), (9), (8), (8), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Surface Plasmon Resonance (SPR)
(1822), (494), (453), (353), (322), (311), (161), (156), (98), (78), (41), (39), (38), (30), (29), (25), (18), (14), (14), (11), (9), (9), (6), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling Images
Purpose Monoclonal antibody to detect CD4 in human and chimpanzee samples.
Purification Affinity purified using protein A
Immunogen Domain 1 of human CD4.
Clone CE9-1
Isotype IgG4 lambda

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background The antibody binds specifically to CD4, a molecule which is part of the immunolgobulin super-family, expressed on the surface of helper T cells. The CD4 Molecule acts as a co-receptor in the activation of T cells, aiding the interaction between the TCR and MHC II of the antigen-presenting cell. The antibody is classified as "primatized", as the variable regions of the light and heavy chains are obtained from primates, while the lamda light chain and γ4 heavy chain constant domains are human. The antibody was engineered from the primatized IgG1 monoclonal antibody Keliximab by substituting two key residues. The role of the antibody as an immunosuppressor has been tested in vivo, by intravenous administration in chimpanzees and human volunteers. The antibody reached Phase II clinical trials with Biogen-Idec.
Synonyms: p55, T cell surface antign T4/Leu-3.
Gene ID 920
UniProt P01730
Research Area Adaptive Immunity, Immunology, Hematopoietic Progenitors, Surface Receptors of Immune Cells, CD Antigens
Pathways TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details Images back to top
Format Liquid
Buffer 200 μg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02 % Proclin 300
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use
Storage -20 °C
Expiry Date 12 months