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|Antigen||CD4 Molecule (CD4) Antibodies|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This CD4 antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
|4 references available|
|Supplier||Log in to see|
Product Details anti-CD4 AntibodyTarget Details CD4 Application Details Handling References for anti-CD4 antibody (ABIN4900717) Images
|Specificity||Reacts with mouse CD4, an antigen co-receptor on the T cell surface which interacts with MHC II molecules on antigen presenting cells.|
|Purification||Protein A or G purified from hybridoma culture supernatant|
|Sterility||0.2 μm filtered|
|Endotoxin Level||<0.10 EU per 1 μg of the antibody by the LAL method.|
|Immunogen||Mouse CTL clone V4|
Target Details CD4Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 antibody (ABIN4900717) Images back to top
|Alternative Name||CD4 (CD4 Antibody Abstract)|
|Background||Alternative Names: CD4, CD4 antigen, CD4 antigen (p55), CD4 Molecule, CD4 receptor, CD4mut, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4|
|Research Area||Surface Receptors of Immune Cells, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Immunology|
|Pathways||TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 antibody (ABIN4900717) Images back to top
Flow Cytometry 2.5 μg/10^6 cells
Immunohistochemistry 1-25 μg/mL
Costimulation of T Cells
Inhibition of T Cell Function
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 antibody (ABIN4900717) Images back to top
|Reconstitution||Reconstitute at 0.5 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-CD4 antibody (ABIN4900717)Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
|Product cited in:||
Aloisio, Nakada, Saatcioglu, Peña, Baker, Tarnawa, Mukherjee, Manjunath, Bugde, Sengupta, Amatruda, Cuevas, Hamra, Castrillon: "PAX7 expression defines germline stem cells in the adult testis." in: The Journal of clinical investigation, Vol. 124, Issue 9, pp. 3929-44, 2014 Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).
Mills, Alabanza, Mahamed, Bynoe: "Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis." in: Journal of neuroinflammation, Vol. 9, pp. 193, 2012 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Mouse (Murine)).
Hokeness, Deweerd, Munks, Lewis, Gladue, Salazar-Mather: "CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection." in: Journal of virology, Vol. 81, Issue 3, pp. 1241-50, 2007 Method employed by authors: Immunohistochemistry (IHC) (Sample species: Mouse (Murine)).
Dajee, Muchamuel, Schryver, Oo, Alleman-Sposeto, De Vry, Prasad, Ruhrmund, Shyamsundar, Mutnick, Mai, Le, Parham, Zhang, Komuves, Colby, Hudak, McEvoy, Ehrhardt: "Blockade of experimental atopic dermatitis via topical NF-kappaB decoy oligonucleotide." in: The Journal of investigative dermatology, Vol. 126, Issue 8, pp. 1792-803, 2006 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Mouse (Murine)).
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