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|Epitope||AA 1-133 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This CD83 antibody is un-conjugated Alternatives|
|2 references available|
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Product Details anti-CD83 AntibodyTarget Details CD83 Application Details Handling References for anti-CD83 antibody (ABIN2001341) Images
|Characteristics||Produced in rabbits immunized with purified, recombinant Mouse CD83 (rM CD83, ABIN2008175 O88324, Met 1-Arg 133,. CD83 specific IgG was purified by Mouse CD83 affinity chromatography.|
|Purification||purified by affinity chromatography|
|Sterility||0.2 μm filtered|
|Immunogen||Recombinant Mouse CD83 protein (ABIN2008175)|
Target Details CD83Product Details anti-CD83 Antibody Application Details Handling References for anti-CD83 antibody (ABIN2001341) Images back to top
|Alternative Name||CD83 (CD83 Antibody Abstract)|
|Background||The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhaunce the rate of tumor growth and inhibit the T cell growth.|
|Research Area||Immunology, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells|
Application DetailsProduct Details anti-CD83 Antibody Target Details CD83 Handling References for anti-CD83 antibody (ABIN2001341) Images back to top
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse CD83-His. The detection limit for Mouse CD83-His is approximately 0.00975 ng/well.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD83 Antibody Target Details CD83 Application Details References for anti-CD83 antibody (ABIN2001341) Images back to top
|Buffer||0.2 μm filtered solution in PBS with 5 % trehalose|
|Handling Advice||Avoid repeated freeze-thaw cycles.|
|Storage||4 °C,-20 °C,-80 °C|
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
|Expiry Date||12 months|
References for anti-CD83 antibody (ABIN2001341)Product Details anti-CD83 Antibody Target Details CD83 Application Details Handling Images back to top
Seto: "Histone modifications." in: Methods (San Diego, Calif.), Vol. 31, Issue 1, pp. 1-2, 2003
Scholler, Hayden-Ledbetter, Dahlin, Hellström, Hellström, Ledbetter: "Cutting edge: CD83 regulates the development of cellular immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 6, pp. 2599-602, 2002