anti-Rat (Rattus) CD86 antibody for ELISA

Recommended CD86 Antibody (supplied by: Log in to see )

Antigen
CD86 Molecule (CD86) Antibodies
  • B7-2
  • B7
  • B7.2
  • B70
  • CLS1
  • Cd28l2
  • ETC-1
  • Ly-58
  • Ly58
  • MB7
  • MB7-2
  • TS/A-2
  • CD28LG2
  • LAB72
  • CD86 molecule
  • CD86 antigen
  • CD86
  • Cd86
Reactivity
Rat (Rattus)
457
425
178
10
6
4
2
2
1
1
Host
Mouse
383
306
114
1
Clonality
Monoclonal
Conjugate
This CD86 antibody is conjugated to Alexa Fluor 647
95
95
55
49
20
13
13
11
10
9
8
7
6
6
5
5
4
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), ELISA
608
266
178
177
134
103
90
69
55
54
43
13
13
12
11
10
8
4
2
2
2
2
1
1
1
1
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Catalog No. ABIN2657855
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN5693207 ELISA WB Rabbit AA 29-248 Log in to see Polyclonal 0
1 ABIN2001593 ELISA Mouse IgG2a AA 1-250 Log in to see 6B4A7 1
1 ABIN2001595 ELISA Rabbit IgG AA 1-250 Log in to see Polyclonal 1
1 ABIN2213462 ELISA Rabbit IgG AA 1-250 Log in to see Polyclonal 0
1 ABIN5702685 ELISA FACS IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5708442 ELISA WB Rabbit IgG Log in to see Polyclonal 0
-12.929095 ABIN4282719 ELISA FACS ICC IF IHC (fro) WB Alexa Fluor 488 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282723 ELISA ICC IF IHC (fro) WB Biotin Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282725 ELISA FACS ICC IF IHC (fro) WB DyLight 680 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282726 ELISA FACS ICC IF IHC (fro) WB DyLight 488 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282724 ELISA FACS ICC IF IHC (fro) WB DyLight 650 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282718 ELISA FACS ICC IF IHC (fro) WB Alexa Fluor 405 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282721 ELISA FACS ICC IF IHC (fro) WB Alexa Fluor 700 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282720 ELISA FACS ICC IF IHC (fro) WB Alexa Fluor 647 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282731 ELISA FACS ICC IF IHC (fro) WB DyLight 550 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282733 ELISA FACS ICC IF IHC (fro) WB DyLight 405 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282728 ELISA FACS ICC IF IHC (fro) WB DyLight 755 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282732 ELISA FACS ICC IF IHC (fro) WB DyLight 350 Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282729 ELISA FACS ICC IF IP WB PerCP Mouse IgG1 kappa Log in to see BU63 0
-12.929095 ABIN4282727 ELISA IHC (fro) WB HRP Mouse IgG1 kappa Log in to see BU63 0

General

Antigen CD86 Molecule (CD86) Antibodies
Reactivity Rat (Rattus)
(457), (425), (178), (10), (6), (4), (2), (2), (1), (1)
Host Mouse
(383), (306), (114), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD86 antibody is conjugated to Alexa Fluor 647
(95), (95), (55), (49), (20), (13), (13), (11), (10), (9), (8), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), ELISA
(608), (266), (178), (177), (134), (103), (90), (69), (55), (54), (43), (13), (13), (12), (11), (10), (8), (4), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-CD86 Antibody

Target Details CD86 Application Details Handling References for anti-CD86 antibody (ABIN2657855) Images
Purification The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone 24F
Isotype IgG1 kappa
Plasmids, Primers & others

Target Details CD86

Product Details anti-CD86 Antibody Application Details Handling References for anti-CD86 antibody (ABIN2657855) Images back to top
Antigen
Alternative Name CD86 (CD86 Antibody Abstract)
Background CD86 is an 80 kD member of the immunoglobulin superfamily also known as B70 or B7-2. It is expressed on antigen presenting cells and activated T and B cells. CD86 is a ligand for CD28 and CD152 (CTLA-4). It is one of the accessory molecules that plays an important role in T cell-APC cell costimulatory interactions. The 24F antibody can block the co-stimulatory activity of CD86.
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation

Application Details

Product Details anti-CD86 Antibody Target Details CD86 Handling References for anti-CD86 antibody (ABIN2657855) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD86 Antibody Target Details CD86 Application Details References for anti-CD86 antibody (ABIN2657855) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C

References for anti-CD86 antibody (ABIN2657855)

Product Details anti-CD86 Antibody Target Details CD86 Application Details Handling Images back to top
Background publications

Donius, Weis, Weis: "Murine complement receptor 1 is required for germinal center B cell maintenance but not initiation." in: Immunobiology, Vol. 219, Issue 6, pp. 440-9, 2014

Carreno, Collins: "The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses." in: Annual review of immunology, Vol. 20, pp. 29-53, 2002

Damoiseaux, Yagita, Okumura, van Breda Vriesman: "Costimulatory molecules CD80 and CD86 in the rat; tissue distribution and expression by antigen-presenting cells." in: Journal of leukocyte biology, Vol. 64, Issue 6, pp. 803-9, 1998

Maeda, Sato, Azuma, Yagita, Okumura: "Characterization of rat CD80 and CD86 by molecular cloning and mAb." in: International immunology, Vol. 9, Issue 7, pp. 993-1000, 1997

Bluestone: "New perspectives of CD28-B7-mediated T cell costimulation." in: Immunity, Vol. 2, Issue 6, pp. 555-9, 1995

Freeman, Borriello, Hodes, Reiser, Hathcock, Laszlo, McKnight, Kim, Du, Lombard: "Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice." in: Science (New York, N.Y.), Vol. 262, Issue 5135, pp. 907-9, 1993

Hathcock, Laszlo, Dickler, Bradshaw, Linsley, Hodes: "Identification of an alternative CTLA-4 ligand costimulatory for T cell activation." in: Science (New York, N.Y.), Vol. 262, Issue 5135, pp. 905-7, 1993

Images

Product Details anti-CD86 Antibody Target Details CD86 Application Details Handling References for anti-CD86 antibody (ABIN2657855) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD86 Molecule (CD86) antibody (Alexa Fluor 647) (ABIN2657855) anti-CD86 Molecule (CD86) antibody (Alexa Fluor 647)