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|Antigen||IL2-Inducible T-Cell Kinase (ITK) Antibodies|
|Epitope||AA 575-617, C-Term Alternatives|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This ITK antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-ITK AntibodyTarget Details ITK Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for Tyrosine-protein kinase ITK/TSK(ITK) detection. Tested with WB in Human,Mouse.|
|Sequence||FRLYKPRLAS THVYQIMNHC WKERPEDRPA FSRLLRQLAE IAE|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Tyrosine-protein kinase ITK/TSK(ITK) detection. Tested with WB in Human,Mouse.
Gene Name: IL2 inducible T-cell kinase
Protein Name: Tyrosine-protein kinase ITK/TSK
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human ITK (575-617aa FRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAE), different from the related mouse sequence by five amino acids.|
|Plasmids, Primers & others|
Target Details ITKProduct Details anti-ITK Antibody Application Details Handling Images back to top
|Alternative Name||ITK (ITK Antibody Abstract)|
Tyrosine-protein kinase ITK/TSK, also known as interleukin-2-inducible T-cell kinase or simply ITK, is a protein that in humans is encoded by the ITK gene. It is a member of the TEC family of kinases. This gene is mapped to 5q33.3. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein is thought to play a role in T-cell proliferation and differentiation. Furthermore, ITK is functionally important for the development and effector function of Th2 and Th17 cells.
Synonyms: EMT | Itk | LPFS1 | LYK | PSCTK 2 | PSCTK2 | TSK | Q08881
|Pathways||TCR Signaling, Fc-epsilon Receptor Signaling Pathway|
Application DetailsProduct Details anti-ITK Antibody Target Details ITK Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-ITK Antibody Target Details ITK Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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