anti-Mouse (Murine) LAT antibody for Immunofluorescence

Recommended LAT Antibody (supplied by: Log in to see )

Antigen
Linker For Activation of T Cells (LAT) Antibodies
  • LAT
  • lat
  • LAT1
  • pp36
  • linker for activation of T-cells
  • linker for activation of T cells
  • LAT
  • lat
  • Lat
Epitope
pTyr161
31
24
24
22
15
10
7
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
296
141
122
3
2
1
Host
Rabbit
178
125
12
2
Clonality
Polyclonal
Conjugate
This LAT antibody is un-conjugated
11
11
8
8
7
6
6
6
5
5
5
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
234
87
60
51
39
35
32
22
15
6
2
2
1
1
1
1
1
1
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Catalog No. ABIN6271566
$ 450.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN6272038 ELISA ICC IF WB Rabbit IgG pTyr255 Log in to see Polyclonal 0
1 ABIN6262916 ELISA ICC IF WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4330360 ICC IF IP WB Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330398 ICC IF WB Alexa Fluor 488 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330400 ICC IF WB Alexa Fluor 647 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330396 ICC IF WB Alexa Fluor 405 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330368 ICC IF WB DyLight 350 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330374 ICC IF IP WB PerCP Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330378 ICC IF WB DyLight 755 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330380 ICC IF WB DyLight 680 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330382 ICC IF WB DyLight 488 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330402 ICC IF WB Alexa Fluor 700 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330370 ICC IF WB DyLight 405 Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330376 ICC IF IP WB APC Mouse IgG2a Log in to see LAT-1D1 0
1 ABIN4330372 ICC IF IP WB PE Mouse IgG2a Log in to see LAT-1D1 0

General

Antigen Linker For Activation of T Cells (LAT) Antibodies
Epitope pTyr161
(31), (24), (24), (22), (15), (10), (7), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(296), (141), (122), (3), (2), (1)
Host Rabbit
(178), (125), (12), (2)
Clonality
Polyclonal
Conjugate This LAT antibody is un-conjugated
(11), (11), (8), (8), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(234), (87), (60), (51), (39), (35), (32), (22), (15), (6), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-LAT Antibody

Target Details LAT Application Details Handling Images
Specificity LAT (Phospho-Tyr161) Antibody detects endogenous levels of LAT only when phosphorylated at Tyr161
Cross-Reactivity Human, Mouse (Murine)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human LAT (Phospho-Tyr161)
Isotype IgG
Plasmids, Primers & others

Target Details LAT

Product Details anti-LAT Antibody Application Details Handling Images back to top
Antigen
Alternative Name LAT (LAT Antibody Abstract)
Background

Description: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Gene: LAT

Molecular Weight 28kDa
Gene ID 27040
UniProt O43561
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-LAT Antibody Target Details LAT Handling Images back to top
Application Notes WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-LAT Antibody Target Details LAT Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months