anti-Cow (Bovine) MXI1 antibody for Western Blotting

Recommended MXI1 Antibody (supplied by: Log in to see )

Antigen
MAX Interactor 1 (MXI1) Antibodies
  • mxi
  • mad2
  • mxd2
  • xmxi1
  • MGC89544
  • MXI1
  • etID309773.22
  • fb16b12
  • fb55f03
  • wu:fb16b12
  • wu:fb55f03
  • wu:fd06a08
  • wu:fz74f10
  • ENSMUSG00000067085
  • Gm10197
  • Mad2
  • bHLHc11
  • MXI-WR
  • MAD2
  • MXD2
  • MXI
  • MAX interactor 1, dimerization protein
  • max interactor 1, dimerization protein
  • MAX interactor 1, dimerization protein L homeolog
  • mxi1
  • MXI1
  • Mxi1
  • mxi1.L
Epitope
Middle Region
11
9
8
7
4
3
3
2
2
2
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Rabbit, Rat (Rattus), Yeast (Saccharomyces cerevisiae), Zebrafish (Danio rerio)
44
37
15
5
4
4
3
3
3
2
2
2
2
1
1
Host
Rabbit
47
10
3
Clonality
Polyclonal
Conjugate
This MXI1 antibody is un-conjugated
3
3
3
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
52
28
7
4
3
3
2
1
1
1
Options
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Available images

Catalog No. ABIN2777279
$ 319.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10.843901 ABIN2779814 WB Rabbit N-Term Log in to see Polyclonal 0
7.8439007 ABIN2777278 WB Rabbit Middle Region Log in to see Polyclonal 1
4 ABIN6749696 IHC IHC (p) WB Rabbit IgG AA 176-225 Log in to see Polyclonal 0
4 ABIN6742204 WB Rabbit AA 215-264 Log in to see Polyclonal 0

General

Antigen MAX Interactor 1 (MXI1) Antibodies
Epitope Middle Region
(11), (9), (8), (7), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Rabbit, Rat (Rattus), Yeast (Saccharomyces cerevisiae), Zebrafish (Danio rerio)
(44), (37), (15), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(47), (10), (3)
Clonality
Polyclonal
Conjugate This MXI1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(52), (28), (7), (4), (3), (3), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-MXI1 Antibody

Target Details MXI1 Application Details Handling References for anti-MXI1 antibody (ABIN2777279) Images
Blocking Peptide Blocking peptide for this product available: ABIN980399
Sequence LNKAKAHIKK LEEAERKSQH QLENLEREQR FLKWRLEQLQ GPQEMERIRM
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 75%, Zebrafish: 79%
Characteristics This is a rabbit polyclonal antibody against MXI1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MXI1
Plasmids, Primers & others

Target Details MXI1

Product Details anti-MXI1 Antibody Application Details Handling References for anti-MXI1 antibody (ABIN2777279) Images back to top
Antigen
Alternative Name MXI1 (MXI1 Antibody Abstract)
Background Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors.Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Alias Symbols: MAD2, MGC43220, MXD2, MXI, bHLHc11
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-9, KRTAP10-7, KRT40, RPL23AP32, CALCOCO2, MAX, ENTPD5, UBC, APP, CDC20, BUB1B, SIN3B, SIN3A, SMC3, MYC,
Protein Size: 295
Molecular Weight 26 kDa
Gene ID 4601
NCBI Accession NM_130439, NP_569157
UniProt P50539
Pathways Maintenance of Protein Location

Application Details

Product Details anti-MXI1 Antibody Target Details MXI1 Handling References for anti-MXI1 antibody (ABIN2777279) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 295 AA

Restrictions For Research Use only

Handling

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details References for anti-MXI1 antibody (ABIN2777279) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MXI1 antibody (ABIN2777279)

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details Handling Images back to top
Background publications

Dugast-Darzacq, Pirity, Blanck, Scherl, Schreiber-Agus: "Mxi1-SRalpha: a novel Mxi1 isoform with enhanced transcriptional repression potential." in: Oncogene, Vol. 23, Issue 55, pp. 8887-99, 2004

Images

Product Details anti-MXI1 Antibody Target Details MXI1 Application Details Handling References for anti-MXI1 antibody (ABIN2777279) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MAX Interactor 1 (MXI1) (Middle Region) antibody (ABIN2777279) IHC Suggested Anti-MXI1 antibody Titration: 5ug/ ml Positive Control: Lung, respirat...
Immunohistochemistry (IHC) image for anti-MAX Interactor 1 (MXI1) (Middle Region) antibody (ABIN2777279) Rabbit Anti-MXI1 Antibody Catalog Number: ARP31403 Paraffin Embedded Tissue: Human Lu...
Western Blotting (WB) image for anti-MAX Interactor 1 (MXI1) (Middle Region) antibody (ABIN2777279) WB Suggested Anti-MXI1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive ...
Western Blotting (WB) image for anti-MAX Interactor 1 (MXI1) (Middle Region) antibody (ABIN2777279) Host: Mouse Target Name: MXI1 Sample Tissue: Mouse Brain Antibody Dilution: 1u...