Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Tnfr1 (show TNFRSF1A Proteins) deletion partially restored thymic and lung macrophages.
TAK1 is required for PPARgamma (show PPARG Proteins) transactivation and promotes PPARgamma (show PPARG Proteins) transcriptional activity synergistically with TAK1 binding protein 1 (TAB1 (show TAB1 Proteins)).
inhibition of TAK1 triggered two caspase 8 (show CASP8 Proteins) activation pathways through the induction of RIP1 (show RALBP1 Proteins)-FADD (show FADD Proteins)-caspase 8 (show CASP8 Proteins) complex as well as FLIP cleavage/degradation.
Transforming growth factor-beta activated kinase 1 (TAK1 (show MAP3K7 Proteins)) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (show FAM126A Proteins)) development.
TAK1 regulates Nrf2 (show NFE2L2 Proteins) through modulation of Keap-p62/SQSTM1 (show SQSTM1 Proteins) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.
CNS-specific Tak1 deletion prevented ER-stress-induced hypothalamic leptin (show LEP Proteins) resistance and hyperphagic obesity under a high-fat diet (HFD). Thus, TAK1 is a crucial regulator of ER stress in vivo, which could be a target for alleviation of ER stress and its associated disease conditions.
SIRT7 inhibits TR4 degradation by deacetylation of DDB1.
this study shows that TAK1 negatively regulates lipopolysaccharide-induced cytokine secretion in myeloid cells by inhibiting MEKK3 (show MAP3K3 Proteins) activities
TR4 binds GR to play an important role in glucocorticoid-directed corticotroph tumor POMC (show POMC Proteins) regulation in addition to modulating glucocorticoid actions on other GR targets.
Mekk1 (show MAP2K1 Proteins) (encoded by Map3k1 (show MAP3K1 Proteins)) signaling activates Mapks to regulate Cdkn1b (show CDKN1B Proteins) (encoding p27(Kip1 (show CDKN1B Proteins))) expression and p27(Kip1 (show CDKN1B Proteins))-dependent proliferative expansion in response to antigen.
High TAK1 (show MAP3K7 Proteins) expression is associated with the progression of hepatocellular carcinoma.
Here, we report that Pseudomonas aeruginosa ExoY inhibits proinflammatory cytokine production through suppressing the activation of TAK1 (show MAP3K7 Proteins) as well as downstream NF-kappaB (show NFKB1 Proteins) and mitogen-activated protein (MAP) kinases.
this study shows that TAP1 (show TAP1 Proteins) plays a novel role in the negative regulation of virus-triggered NF-kappaB (show NFKB1 Proteins) signaling and the innate immune response by targeting the TAK1 (show MAP3K7 Proteins) complex
TAK1 (show MAP3K7 Proteins)/TAB1 (show TAB1 Proteins) expression in non-small cell lung carcinoma tissue is significantly increased and closely associated with patient clinical prognosis.
miR (show MLXIP Proteins)-203 represses NF-kappaB (show NFKB1 Proteins) signaling via targeting TAK1 (show MAP3K7 Proteins) and PI3KCA and miR (show MLXIP Proteins)-203 overexpression may contribute to the COPD (show ARCN1 Proteins) initiation.
DK1 inhibits the formation of the TAK1 (show MAP3K7 Proteins)-TAB2 (show TAB2 Proteins)-TRAF6 (show TRAF6 Proteins) complex and leads to the inhibition of TRAF6 (show TRAF6 Proteins) ubiquitination.
IFIT5 promotes SeV-induced IKK (show CHUK Proteins) phosphorylation and NF-kappaB (show NFKB1 Proteins) activation by regulating the recruitment of IKK (show CHUK Proteins) to TAK1 (show MAP3K7 Proteins).
USP18 (show USP18 Proteins) negatively regulates NF-kappaB (show NFKB1 Proteins) signaling by targeting TAK1 (show MAP3K7 Proteins) and NEMO (show IKBKG Proteins) for deubiquitination through distinct mechanisms.
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996
TGF-beta activated kinase 1
, mitogen-activated protein kinase kinase kinase 7
, TGF-beta-activated kinase 1
, mitogen activated protein kinase kinase kinase 7
, transforming growth factor beta-activated kinase 1
, transforming growth factor-beta-activated kinase 1
, Nuclear hormone receptor TR4
, TR4 nuclear hormone receptor
, nuclear receptor subfamily 2 group C member 2
, orphan nuclear receptor TAK1
, orphan nuclear receptor TR4
, testicular nuclear receptor 4
, testicular receptor 4
, nuclear receptor subfamily 2, group H, member 2
, orphan receptor, TR4
, TR4 orphan receptor
, TR4-NS orphan receptor
, orphan receptor TR4