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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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16.751959 | ABIN2779600 | IHC WB | Rabbit | N-Term | Log in to see | Polyclonal | 1 |
General |
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Antigen | RuvB-Like 2 (E. Coli) (RUVBL2) Antibodies |
Epitope | N-Term Alternatives |
Reactivity | Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This RUVBL2 antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
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2 references available |
Supplier | Log in to see |
Product Details anti-RUVBL2 AntibodyTarget Details RUVBL2 Application Details Handling References for anti-RUVBL2 antibody (ABIN2779601) Images |
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Blocking Peptide | Blocking peptide for this product available: ABIN983337 |
Sequence | IDRPATGTGS KVGKLTLKTT EMETIYDLGT KMIESLTKDK VQAGDVITID |
Predicted Reactivity | Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93% |
Characteristics | This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2 |
Plasmids, Primers & others | |
Target Details RUVBL2Product Details anti-RUVBL2 Antibody Application Details Handling References for anti-RUVBL2 antibody (ABIN2779601) Images back to top |
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Antigen | |
Alternative Name | RUVBL2 (RUVBL2 Antibody Abstract) |
Background |
RUVBL2 encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. Alias Symbols: RVB2, TIH2, ECP51, TIP48, CGI-46, INO80J, REPTIN, TIP49B Protein Interaction Partner: CCDC103, LNX1, RUVBL1, UBC, DPCD, HUWE1, VCP, SUMO2, RPAP3, MDM2, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, CDKN2A, ASNA1, PPP6R3, PLA2G4A, PARK2, FBXO6, TARDBP, YWHAQ, PPP6R2, EXOSC10, BAG3, POLR2E, UPF1, SMG1, RBM8A, TTI1, PAN2, TBP, CTNNB1, STOM, RUVBL Protein Size: 463 |
Molecular Weight | 51 kDa |
Gene ID | 10856 |
NCBI Accession | NM_006666, NP_006657 |
UniProt | Q9Y230 |
Pathways | Telomere Maintenance |
Application DetailsProduct Details anti-RUVBL2 Antibody Target Details RUVBL2 Handling References for anti-RUVBL2 antibody (ABIN2779601) Images back to top |
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Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 463 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-RUVBL2 Antibody Target Details RUVBL2 Application Details References for anti-RUVBL2 antibody (ABIN2779601) Images back to top |
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Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-RUVBL2 antibody (ABIN2779601)Product Details anti-RUVBL2 Antibody Target Details RUVBL2 Application Details Handling Images back to top |
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Product cited in: |
Barthéléry, Jaishankar, Salli, Vrana: "Reptin52 expression during in vitro neural differentiation of human embryonic stem cells." in: Neuroscience letters, Vol. 452, Issue 1, pp. 47-51, 2009 |
Background publications |
Bauer, Chauvet, Huber, Usseglio, Rothbächer, Aragnol, Kemler, Pradel: "Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity." in: The EMBO journal, Vol. 19, Issue 22, pp. 6121-30, 2000 |
ImagesProduct Details anti-RUVBL2 Antibody Target Details RUVBL2 Application Details Handling References for anti-RUVBL2 antibody (ABIN2779601) back to top |
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Supplier Images |
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