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|Antigen||Glutathione Reductase (GSR) Antibodies|
|Epitope||AA 256-522 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Glutathione Reductase antibody is un-conjugated Alternatives|
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
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Product Details anti-Glutathione Reductase AntibodyTarget Details Glutathione Reductase Application Details Handling Images
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
|Characteristics||Rabbit IgG polyclonal antibody for Glutathione Reductas detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.|
|Immunogen||E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).|
|Plasmids, Primers & others|
Target Details Glutathione ReductaseProduct Details anti-Glutathione Reductase Antibody Application Details Handling Images back to top
|Alternative Name||GSR (GSR Antibody Abstract)|
Synonyms: Glutathione reductase, mitochondrial, GR, GRase, GSR, GLUR, GRD1
Background: Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
|Pathways||Thyroid Hormone Synthesis, Cell RedoxHomeostasis|
Application DetailsProduct Details anti-Glutathione Reductase Antibody Target Details Glutathione Reductase Handling Images back to top
Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.
|Restrictions||For Research Use only|
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|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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