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anti-Rat (Rattus) GPX8 Antibodies:
anti-Human GPX8 Antibodies:
anti-Mouse (Murine) GPX8 Antibodies:
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Study provides evidence that the conserved N-terminal transmembrane domain of GPX8, in addition to its enzymatic activity, is essential for regulating Ca(2 (show CA2 Antibodies)+) dynamics revealing a novel level of integration between redox-related proteins and Ca(2 (show CA2 Antibodies)+) signaling/homeostasis.
GPX8 is transcriptionally regulated by HIFalpha and modulates growth factor signaling in HeLa cells.
Along with the induction of GPX8 in ER-stressed cells, these findings question a ubiquitous role of Ero1alpha as a producer of cytoplasmic ROS (show ROS1 Antibodies) under ER stress
Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease.
GPx8 labeled as secreted glutathione peroxidase (show GPX1 Antibodies), is actually endoplasmic reticulum-resident protein disulfide isomerase (show P4HB Antibodies) peroxidase
the deficiency of AtGPX8 accelerates the progression of oxidative stress in knockout out plants.
These results suggest that AtGPX8 plays an important role in the protection of cellular components including nuclear DNA against oxidative stress.
May constitute a glutathione peroxidase-like protective system against oxidative stresses (By similarity).
probable glutathione peroxidase 8