anti-Rat (Rattus) IRF7 antibody for ELISA

Recommended IRF7 Antibody (supplied by: Log in to see )

Antigen
Interferon Regulatory Factor 7 (IRF7) Antibodies
  • wu:fl24c03
  • zgc:66043
  • zgc:77947
  • IRF7
  • irf7
  • IRF-7H
  • IRF7A
  • IRF7B
  • IRF7C
  • IRF7H
  • interferon regulatory factor 7
  • irf7
  • IRF7
  • Irf7
Reactivity
Human, Mouse (Murine), Rat (Rattus)
149
59
55
3
2
2
2
2
1
1
Host
Rabbit
107
42
Clonality
Polyclonal
Conjugate
This IRF7 antibody is un-conjugated
7
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
103
50
27
26
24
10
6
5
4
2
2
1
1
1
Supplier
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Available images

Catalog No. ABIN6262657
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN1030452 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
7 ABIN5545934 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
7 ABIN2431541 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
5.5 ABIN1002560 IHC ELISA WB Rabbit IgG C-Term Log in to see Polyclonal 4
4 ABIN6272122 ELISA WB Rabbit IgG pSer477 Log in to see Polyclonal 0
1 ABIN1887368 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0

General

Antigen Interferon Regulatory Factor 7 (IRF7) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(149), (59), (55), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(107), (42)
Clonality
Polyclonal
Conjugate This IRF7 antibody is un-conjugated
(7), (6), (6), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
(103), (50), (27), (26), (24), (10), (6), (5), (4), (2), (2), (1), (1), (1)
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Product Details anti-IRF7 Antibody

Target Details IRF7 Application Details Handling Images
Specificity IRF7 Antibody detects endogenous levels of total IRF7
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human IRF7
Isotype IgG
Plasmids, Primers & others

Target Details IRF7

Product Details anti-IRF7 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IRF7 (IRF7 Antibody Abstract)
Background

Description: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. Exists in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization where along with other coactivators it can activate transcription of the type I IFN and ISG genes. Can also play a role in regulating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or through induction of IRF1. Binds to the Q promoter (Qp) of EBV nuclear antigen 1 a (EBNA1) and may play a role in the regulation of EBV latency. Can activate distinct gene expression programs in macrophages and regulate the anti-tumor properties of primary macrophages.

Gene: IRF7

Molecular Weight 54 kDa
Gene ID 3665
UniProt Q92985
Pathways TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy

Application Details

Product Details anti-IRF7 Antibody Target Details IRF7 Handling Images back to top
Application Notes WB 1:1000-3000 IHC 1:200
Restrictions For Research Use only

Handling

Product Details anti-IRF7 Antibody Target Details IRF7 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-IRF7 Antibody Target Details IRF7 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Interferon Regulatory Factor 7 (IRF7) antibody (ABIN6262657) Western blot analysis IRF7 using 293 whole cell lysates
Immunohistochemistry (IHC) image for anti-Interferon Regulatory Factor 7 (IRF7) antibody (ABIN6262657) ABIN6277717 at 1/100 staining Human liver tissue by IHC-P. The sample was formaldehyd...