anti-Mouse (Murine) TAB1 antibody for Enzyme Immunoassay

Recommended TAB1 Antibody (supplied by: Log in to see )

Antigen
TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antibodies
  • 3'-Tab1
  • MAP3K7IP1
  • 2310012M03Rik
  • Map3k7ip1
  • b2b449Clo
  • TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1
  • TAB1
  • Tab1
Epitope
Center
31
11
10
10
9
9
8
6
5
5
5
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
184
82
64
8
6
5
4
3
3
2
1
1
1
1
Host
Rabbit
157
25
2
Clonality
Polyclonal
Conjugate
This TAB1 antibody is un-conjugated
9
9
8
6
6
6
3
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
133
78
27
21
18
14
12
12
9
3
2
2
1
Supplier
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Catalog No. ABIN5555289
$ 474.10
Plus shipping costs $45.00

General

Antigen TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antibodies
Epitope Center
(31), (11), (10), (10), (9), (9), (8), (6), (5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(184), (82), (64), (8), (6), (5), (4), (3), (3), (2), (1), (1), (1), (1)
Host Rabbit
(157), (25), (2)
Clonality
Polyclonal
Conjugate This TAB1 antibody is un-conjugated
(9), (9), (8), (6), (6), (6), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(133), (78), (27), (21), (18), (14), (12), (12), (9), (3), (2), (2), (1)
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Product Details anti-TAB1 Antibody

Target Details TAB1 Application Details Handling Images
Specificity This antibody detects TAB1 / MAP3K7IP1.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Peptide affinity chromatography
Immunogen TAB1 antibody was raised against a synthetic peptide corresponding to 13 amino acids in the center of human TAB1.
Isotype IgG
Plasmids, Primers & others

Target Details TAB1

Product Details anti-TAB1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TAB1 / MAP3K7IP1 (TAB1 Antibody Abstract)
Background TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7 (1), which is known to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily (2), thus acting as an intermediate in both proliferative and innate and adaptive immune responses (3). This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals (4,5). It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF-beta, demonstrating how this protein can function as a mediator between TGF-beta receptors and TAK1 (6).Synonyms: Mitogen-activated protein kinase kinase kinase 7-interacting protein 1, TAK1-binding protein 1, TGF-beta-activated kinase 1-binding protein 1
Gene ID 10454
NCBI Accession NP_006107
Pathways TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-TAB1 Antibody Target Details TAB1 Handling Images back to top
Application Notes ELISA. Western blot: 0.5 to 1 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TAB1 Antibody Target Details TAB1 Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.