anti-Human TLR5 antibody for Flow Cytometry

Recommended TLR5 Antibody (supplied by: Log in to see )

Antigen
Toll-Like Receptor 5 (TLR5) Antibodies
  • SLEB1
  • TIL3
  • TLR-5
  • sleb1
  • til3
  • tlr-5
  • tlr5
  • toll like receptor 5
  • toll-like receptor 5
  • toll like receptor 5 L homeolog
  • toll-like receptor 5b
  • TLR5
  • Tlr5
  • tlr5.L
  • tlr-5
  • tlr5b
Epitope
AA 261-420
33
15
14
11
11
11
11
10
7
7
7
5
5
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
243
147
48
43
5
2
2
2
1
Host
Mouse
167
92
4
Clonality
Monoclonal
Conjugate
This TLR5 antibody is conjugated to FITC
21
17
12
9
8
5
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
208
92
83
70
64
19
16
13
11
10
6
4
3
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN5564260
$ 596.56
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.572235 ABIN5564259 FACS IHC Mouse IgG2a AA 261-420 Log in to see ABM22G1 0
12.363859 ABIN4900606 CyTOF FACS IHC Mouse IgG1 AA 21-115 Log in to see 624915 0
10 ABIN208231 FACS IHC IHC (fro) WB Mouse IgG2a AA 700-800 Log in to see 19D759-2 0
9.363859 ABIN4898067 FACS Alexa Fluor 488 Mouse IgG1 AA 21-115 Log in to see 624915 0
7 ABIN959419 FACS IHC IHC (p) WB Rabbit IgG AA 300-350 Log in to see Polyclonal 0
7 ABIN956813 FACS FITC Mouse IgG2a Log in to see 85B152-5 0
7 ABIN959941 FACS PE Mouse IgG2a, kappa Log in to see 85B152-5 0
7 ABIN208236 FACS WB Mouse IgG2a Log in to see 85B152-5 0
4 ABIN956810 FACS FITC Mouse IgG2a, kappa AA 700-800 Log in to see 19D759-2 0
4 ABIN960422 FACS PE Mouse IgG2a, kappa AA 700-800 Log in to see 19D759-2 0
4 ABIN1740119 FACS IHC (p) WB Rabbit IgG AA 300-350 Log in to see Polyclonal 0
1 ABIN342758 ICC FACS IHC ELISA WB Goat AA 151-181 Log in to see Polyclonal 0
1 ABIN1821324 FACS IHC Mouse IgG1 AA 21-115 Log in to see GL-3-5E11 0
1 ABIN2376355 FACS PE Mouse IgG2a kappa AA 700-800 Log in to see 11E374 0
1 ABIN2376353 FACS FITC Mouse IgG2a kappa AA 700-800 Log in to see 11E374 0
1 ABIN2376360 IC FACS IHC WB Goat AA 151-181 Log in to see Polyclonal 0
1 ABIN2770126 FACS IHC (p) WB Rabbit IgG AA 300-350 Log in to see Polyclonal 0
1 ABIN2376354 FACS PE Mouse IgG2a kappa Log in to see 11E373 0
1 ABIN2376352 FACS FITC Mouse IgG2a Log in to see 11E373 0
1 ABIN2376356 FACS IHC WB Mouse IgG2a kappa AA 700-800 Log in to see 4H281 0

General

Antigen Toll-Like Receptor 5 (TLR5) Antibodies
Epitope AA 261-420
(33), (15), (14), (11), (11), (11), (11), (10), (7), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(243), (147), (48), (43), (5), (2), (2), (2), (1)
Host Mouse
(167), (92), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TLR5 antibody is conjugated to FITC
(21), (17), (12), (9), (8), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(208), (92), (83), (70), (64), (19), (16), (13), (11), (10), (6), (4), (3), (1)
Supplier Log in to see

Product Details anti-TLR5 Antibody

Target Details TLR5 Application Details Handling Images
Specificity Recognizes human TLR5.
Cross-Reactivity Human
Purification Protein G purified.
Immunogen Recombinant human TLR5 protein (aa 261-420).
Clone ABM22G1
Isotype IgG2a
Plasmids, Primers & others

Target Details TLR5

Product Details anti-TLR5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TLR5 (TLR5 Antibody Abstract)
Background TLR5 (Toll-like Receptor 5) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR5 recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor, via a conserved region within flagellin, the D1 portion/domain. Binding of flagellin induces the dimerization of TLR5, which in turn recruits MyD88. The recruitment of MyD88 leads to subsequent activation of IRAK4, IRAK1, TRAF6 and eventually IkappaB kinases. Activation of IkappaB kinases mobilizes the nuclear factor NF-kappaB and stimulates many downstream gene expressions, which initiate the canonical proinflammatory pathway, including TNF-alpha production. TLR5 may play a role in inflammatory bowel disease (IBD). Lower levels of TLR5 expression have been found in patients exhibiting moderate to severe ulcerative colitis (UC). TLR5 is suggested to be possibly involved in HPV induced inflammation and subsequent cervical neoplasia formation. It has been reported that TLR5 expression is detected in both ovarian epithelium and ovarian cancer cell lines, suggesting a possible role of TLR5 in inflammation induced ovarian cancer onset. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus and susceptibility to legionnaire disease, highlighting the importance of TLR5 in microbial recognition particularly at the mucosal surface.
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Application Details

Product Details anti-TLR5 Antibody Target Details TLR5 Handling Images back to top
Restrictions For Research Use only

Handling

Product Details anti-TLR5 Antibody Target Details TLR5 Application Details Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer In 10 mM TRIS containing 150 mM NaCl and 0.05 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: +4°C
Stable for at least 6 months after receipt when stored at +4°C.
Expiry Date 6 months