anti-Human TLR6 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TLR6 Antibody (supplied by: Log in to see )

Antigen
Toll-Like Receptor 6 (TLR6) Antibodies
  • TLR1
  • TLR16
  • CD286
  • TLR-6
  • toll-like receptor 1 family member A
  • toll like receptor 6
  • toll-like receptor 6
  • TLR1A
  • TLR6
  • Tlr6
Epitope
AA 340-380
24
18
11
11
11
9
9
7
7
6
6
5
5
5
4
3
3
3
3
2
2
2
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
193
67
9
3
3
2
1
1
Host
Rabbit
132
74
14
Clonality
Polyclonal
Conjugate
This TLR6 antibody is un-conjugated
19
17
13
7
7
5
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
119
99
82
82
53
22
16
16
6
5
5
2
2
1
1
Options
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Catalog No. ABIN749573
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.5 ABIN388338 FACS IHC (p) WB Rabbit Ig Fraction AA 393-423, C-Term Log in to see Polyclonal 1
14.117413 ABIN214529 ELISA IHC IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal 0
11.5 ABIN531987 FACS IHC (p) Mouse IgG1 Log in to see 86B1153-2 1
11.117413 ABIN214000 ICC IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
10 ABIN357053 EIA IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal 2
10 ABIN357055 EIA IHC (p) Rabbit Ig Fraction C-Term Log in to see Polyclonal 2
10 ABIN388340 IHC (p) WB Rabbit Ig Fraction AA 722-753, C-Term Log in to see Polyclonal 0
10 ABIN5535024 IHC (p) WB Rabbit Ig Fraction AA 722-753, C-Term Log in to see Polyclonal 0
7 ABIN357054 EIA IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal 2
7 ABIN1539419 IHC (p) WB Rabbit Ig AA 1-30, N-Term Log in to see Polyclonal 0
7 ABIN1740122 IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal 0
7 ABIN2682652 IHC (p) Rabbit IgG Center Log in to see Polyclonal 0
7 ABIN5774057 FACS IHC (p) FITC Mouse IgG1 AA 408-424 Log in to see 86B1153-2 0
7 ABIN303301 IHC (p) WB Rabbit Center Log in to see Polyclonal 0
4 ABIN957517 IHC IHC (p) Rabbit AA 25-39 Log in to see Polyclonal 0
4 ABIN1740121 ICC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN302880 IF IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN5555339 EIA IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
1 ABIN1724250 FACS IHC (p) FITC Mouse IgG1 AA 408-424 Log in to see 86B1153-2 0
1 ABIN1840802 FACS IHC IHC (p) WB Rabbit AA 393-423 Log in to see Polyclonal 0

General

Antigen Toll-Like Receptor 6 (TLR6) Antibodies
Epitope AA 340-380
(24), (18), (11), (11), (11), (9), (9), (7), (7), (6), (6), (5), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(193), (67), (9), (3), (3), (2), (1), (1)
Host Rabbit
(132), (74), (14)
Clonality
Polyclonal
Conjugate This TLR6 antibody is un-conjugated
(19), (17), (13), (7), (7), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(119), (99), (82), (82), (53), (22), (16), (16), (6), (5), (5), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-TLR6 Antibody

Target Details TLR6 Application Details Handling References for anti-TLR6 antibody (ABIN749573) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human TLR6
Isotype IgG
Plasmids, Primers & others

Target Details TLR6

Product Details anti-TLR6 Antibody Application Details Handling References for anti-TLR6 antibody (ABIN749573) Images back to top
Antigen
Alternative Name Tlr6 (TLR6 Antibody Abstract)
Background

Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Subcellular location: Extracellular

Synonyms: CD286, Toll-like receptor 6, TLR6

Gene ID 10333
UniProt Q9Y2C9
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Application Details

Product Details anti-TLR6 Antibody Target Details TLR6 Handling References for anti-TLR6 antibody (ABIN749573) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-TLR6 Antibody Target Details TLR6 Application Details References for anti-TLR6 antibody (ABIN749573) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-TLR6 antibody (ABIN749573)

Product Details anti-TLR6 Antibody Target Details TLR6 Application Details Handling Images back to top
Product cited in:

Shmuel-Galia, Aychek, Fink, Porat, Zarmi, Bernshtein, Brenner, Jung, Shai: "Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis." in: The EMBO journal, Vol. 35, Issue 6, pp. 685-98, 2016

Images

Product Details anti-TLR6 Antibody Target Details TLR6 Application Details Handling References for anti-TLR6 antibody (ABIN749573) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-TLR6/CD286 Polyc...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Rat splenocytes stained with Anti- TLR6/CD286 Polyclonal Antibody, PE-CY5.5 Conjugate...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Rat splenocytes stained with Anti- TLR6/CD286 Polyclonal Antibody, PE-CY5.5 Conjugate...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-TLR6 Poly...
Western Blotting (WB) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Rat spleen lysates probed with TLR6 Polyclonal Antibody, unconjugated at 1:300 overn...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Mouse splenocytes probed with TLR6 Polyclonal Antibody, Unconjugated at 1:100 for 30...
Western Blotting (WB) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) Mouse thymus lysates probed with TLR6 Polyclonal Antibody, unconjugated at 1:300 ove...
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) (AA 340-380) antibody (ABIN749573) A549 cells probed with TLR6 Polyclonal Antibody, Unconjugated at 1:100 for 30 minute...