anti-Human TNFAIP3 antibody for ELISA

Recommended TNFAIP3 Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antibodies
  • tnfaip3
  • MGC82339
  • TNFAIP3
  • A20
  • OTUD7C
  • TNFA1P2
  • Tnfip3
  • TNF alpha induced protein 3
  • TNF alpha induced protein 3 S homeolog
  • tumor necrosis factor, alpha-induced protein 3
  • TNFAIP3
  • tnfaip3.S
  • Tnfaip3
Reactivity
Human, Mouse (Murine), Rat (Rattus)
103
67
64
6
2
1
1
Host
Rabbit
72
25
6
Clonality
Polyclonal
Conjugate
This TNFAIP3 antibody is un-conjugated
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
74
38
35
30
28
26
19
13
10
6
3
2
2
2
Supplier
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Catalog No. ABIN6265632
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN2889421 IF ELISA WB Rabbit IgG AA 321-370 Log in to see Polyclonal 0
7 ABIN604690 ELISA IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
7 ABIN1031138 IHC ELISA WB Rabbit Middle Region Log in to see Polyclonal 0
7 ABIN1030759 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
7 ABIN5589783 ELISA IHC WB Rabbit Log in to see Polyclonal 0
7 ABIN5589782 ELISA IHC WB Rabbit Log in to see Polyclonal 0
4 ABIN1740182 IHC (p) ELISA WB Rabbit IgG C-Term Log in to see Polyclonal 0
4 ABIN478080 IHC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
4 ABIN563210 ELISA WB Mouse AA 691-790, partial Log in to see Polyclonal 0
1 ABIN2747660 ELISA WB FITC Rabbit IgG AA 690-790 Log in to see Polyclonal 0
1 ABIN2747659 ELISA WB Rabbit IgG AA 690-790 Log in to see Polyclonal 0
1 ABIN2377432 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN2377427 IF IHC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN2377430 IF IHC ELISA WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN6084879 ELISA HRP Rabbit IgG AA 97-183 Log in to see Polyclonal 0
1 ABIN6084881 ELISA FITC Rabbit IgG AA 97-183 Log in to see Polyclonal 0
1 ABIN6084883 ELISA Biotin Rabbit IgG AA 97-183 Log in to see Polyclonal 0
1 ABIN5878733 ELISA IF/ICC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN6101772 ELISA IF/ICC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN6060365 ELISA IF/ICC WB Rabbit IgG AA 97-183 Log in to see Polyclonal 0

General

Antigen Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(103), (67), (64), (6), (2), (1), (1)
Host Rabbit
(72), (25), (6)
Clonality
Polyclonal
Conjugate This TNFAIP3 antibody is un-conjugated
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(74), (38), (35), (30), (28), (26), (19), (13), (10), (6), (3), (2), (2), (2)
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Product Details anti-TNFAIP3 Antibody

Target Details TNFAIP3 Application Details Handling Images
Specificity TNFAIP3 Antibody detects endogenous levels of total TNFAIP3
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human TNFAIP3
Isotype IgG
Plasmids, Primers & others

Target Details TNFAIP3

Product Details anti-TNFAIP3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TNFAIP3 (TNFAIP3 Antibody Abstract)
Background

Description: Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways, affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG, the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin, polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death. Has a role in the function of the lymphoid system. Required for LPS-induced production of proinflammatory cytokines and IFN beta in LPS-tolerized macrophages.

Gene: TNFAIP3

Molecular Weight 90kDa
Gene ID 7128
UniProt P21580
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-TNFAIP3 Antibody Target Details TNFAIP3 Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-TNFAIP3 Antibody Target Details TNFAIP3 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-TNFAIP3 Antibody Target Details TNFAIP3 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) Western blot analysis of Hepg2 whole cell lysates, using TNFAIP3 Antibody. The lane ...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) ABIN6277109 staining RAW264.7 cells by IF/ICC. The sample were fixed with PFA and pe...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) ABIN6277109 at 1/100 staining Rat kidney tissue by IHC-P. The sample was formaldehyde...
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN6265632) Western blot analysis of extracts from various samples, using TNFAIP3 Antibody. Lane...