Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
A20 regulates canonical wnt (show WNT2 Proteins)-signaling through an interaction with RIPK4 (show RIPK4 Proteins)
these results suggested that in human colorectal cancer cells, A20 may function to inhibit cancer progression via down-regulation of TNFalpha (show TNF Proteins)-induced chemokine (show CCL1 Proteins) production by suppression of ERK (show EPHB2 Proteins) signaling
A20 was significantly downregulated while p-p65 (RelA (show NFkBP65 Proteins)) significantly upregulated in the radioresistant nasopharyngeal carcinoma (NPC (show NPC1 Proteins))relative to radiosensitive NPCs, and miR (show MLXIP Proteins)-125b expression level was negatively associated with A20 expression level, whereas positively associated with p-p65 (RelA (show NFkBP65 Proteins)) level
Low A20 expression is associated with HIV disease.
Gene polymorphisms of TNF (show TNF Proteins)-238G/A, TNF (show TNF Proteins)-308G/A, IL10 (show IL10 Proteins)-1082G/A, TNFAIP3, and MC4R (show MC4R Proteins) and comorbidity occurrence in a Romanian population with psoriasis
A20 overexpression in vivo significantly reduced renal injury as demonstrated by the improved levels of Scr and BUN and the reduction in histological damage.
the risk allele for the TNFAIP3 rs2230926 polymorphism was associated with systemic lupus erythematosus susceptibility.
It was concluded that the A20 protein in macrophages modulates lung injury induced by LPS (show IRF6 Proteins). The overexpression of A20 in macrophages may be involved in modulating macrophage polarization.
TNF (show TNF Proteins) phase III signalling displays ongoing TNFR1 (show TNFRSF1A Proteins)/NF-kappa B (show NFKB1 Proteins) activation in monocytic cells. High- and low-sensitive genes are induced including differentially regulated A20. A20 strictly controls this signalling in an IKK (show CHUK Proteins)- and partially RIP (show HRB Proteins)-dependent manner. The A20-mediated control mechanisms are supported by ABIN1 (show TNIP1 Proteins) and CYLD (show CYLD Proteins).
A20 is a negative regulator of inflammation in human myometrium and foetal membranes.
T cell-specific A20 limited the expansion but reduced apoptosis and necroptosis of Listeria-specific CD8 (show CD8A Proteins)(+) T cells, resulting in an impaired pathogen control in primary but improved clearance in secondary infection.
study reveals a critical role of IL-17RC (show IL17RC Proteins) in maintaining baseline A20 production and a novel role of the IL-17RC (show IL17RC Proteins)-A20 axis in controlling JNK (show MAPK8 Proteins) isoform-dependent tumor-specific homeostatic proliferation.
The data demonstrate that miR (show MLXIP Proteins)-125b regulates nasopharyngeal carcinoma cell proliferation and apoptosis by targeting A20/NF-kappaB (show NFKB1 Proteins) signaling pathway, and miR (show MLXIP Proteins)-125b acts as oncogene (show RAB1A Proteins), whereas A20 functions as tumor suppressor.
Mice with A20 deficient B cells are prone to food allergy.
Tnfaip3, an anti-inflammatory gene, is located precisely underneath the linkage peak and contains two non-synonymous SNPs leading to conservative amino acid substitutions.
Hepatitis C virus core protein ligates gC1qR (show C1QBP Proteins) to induce A20 expression in macrophages via P38 (show CRK Proteins), JNK (show MAPK8 Proteins) and NF-kappaB (show NFKB1 Proteins) signaling pathways, which leads to a low-grade chronic inflammation during HCV infection.
These results suggest that Leishmania exploits A20 and UCP2 (show UCP2 Proteins) to impair inflammasome activation for disease propagation
A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1 (show SNAI1 Proteins).
holding thymic production of natural Treg cells in check, A20 integrates Treg cell activity and increased effector T cell survival into an efficient CD4 (show CD4 Proteins)(+) T cell response
these studies establish A20 as a crucial hepatoprotective factor.
Data show the characterization and deduced amino acid sequence analysis for A20 gene which expression increases in MDBK cells infected by BVDV-1. Also, regulatory regions for NF-kappaB (show NFKB1 Proteins) and Sp-1 (show SP1 Proteins) additionally to an ARE element for mRNA stability were detected
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
tumor necrosis factor, alpha-induced protein 3
, OTU domain-containing protein 7C
, TNF alpha-induced protein 3
, putative DNA-binding protein A20
, tumor necrosis factor alpha-induced protein 3
, tumor necrosis factor inducible protein A20
, zinc finger protein A20
, tumor necrosis factor induced protein 3