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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
ATPase, H+ transporting, V1 subunit B
, ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa
, V-ATPase subunit B 2
, V-type proton ATPase subunit B, brain isoform
, endomembrane proton pump 58 kDa subunit
, vacuolar H+ATPase B2
, vacuolar proton pump subunit B 2
, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B
, vacuolar H-ATPase B subunit osteoclast isozyme
, H+ transporting two-sector ATPase
, V-ATPase B2 subunit
, vacuolar H+-ATPase 56,000 subunit
, H+-ATPase B subunit
, H+-ATPase non-catalytic subunit B
, vacuolar H+-ATPase
, Vacuolar ATP synthase subunit B, brain isoform
, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
, ATPase, H+ transporting, lysosomal, V1 subunit B, member b
, ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B
, lysosomal 56/58kDa