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Human Polyclonal CFL1/2 Primary Antibody for IHC - ABIN362442
Chen, Cizeau, Vande Velde, Park, Bozek, Bolton, Shi, Dubik, Greenberg: Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. in The Journal of biological chemistry 1999
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Human Polyclonal CFL1/2 Primary Antibody for IF, IHC - ABIN363074
Arber, Barbayannis, Hanser, Schneider, Stanyon, Bernard, Caroni: Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. in Nature 1998
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High CFL1 (show VPS72 Antibodies) expression is associated with malignant pancreatic lesions.
High CFL1 (show VPS72 Antibodies) expression is associated with epithelial-mesenchymal transition of gastric cancer.
Cofilin-1 (show CFL1 Antibodies) plays a dominant role in angiotensin-(1-7)-induced G0/G1 arrest and autophagy to maintain cellular homeostasis in human aortic endothelial cells
NKCC1 (show SLC12A2 Antibodies) not only controls cell volume and Cl- concentration, but it can also regulate the actin cytoskeleton through Cofilin 1 (show CFL1 Antibodies).
The enhancement of cancer cells invasion is dependent on CFL1 (show VPS72 Antibodies), a known regulator of invadopodia maturation.
The present study demonstrates that miR (show MLXIP Antibodies)-145 plays an important role in inhibiting cell migration by directly targeting PAK4 (show PAK4 Antibodies), and identifies miR (show MLXIP Antibodies)-145-PAK4 (show PAK4 Antibodies)-LIMK1 (show LIMK1 Antibodies)-cofilin (show CFL1 Antibodies) as a novel regulatory pathway that contributed to colorectal cancer metastasis.
D44 and RHOA (show RHOA Antibodies) are required for CFL1 (show VPS72 Antibodies) phosphorylation and cell migration induced by CD74 (show CD74 Antibodies) in breast cancer cells.
Our results revealed that CKS1 (show CKS1B Antibodies) is involved in normal glutamatergic synapse development and dendritic spine maturation in adult hippocampus through modulating p27 (show PAK2 Antibodies) stability.
Our study indicates that Cofilin 1 (show CFL1 Antibodies) holds an important position in the development and progression of human bladder cancer
Results suggest that the immune-complex (IC) of cofilin-1 (show CFL1 Antibodies) in sera is a potentially attractive serum biomarker for the prognosis of pancreatic ductal adenocarcinoma (PDAC).
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
18 kDa phosphoprotein
, cofilin, non-muscle isoform