anti-Mouse (Murine) Adenomatous Polyposis Coli antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Adenomatous Polyposis Coli Antibody (supplied by: Log in to see )

Antigen
Adenomatous Polyposis Coli (APC) Antibodies
  • dp2
  • dp3
  • fap
  • fpc
  • xapc
  • dp2.5
  • AI047805
  • AU020952
  • AW124434
  • CC1
  • Min
  • mAPC
  • BTPS2
  • DP2
  • DP2.5
  • DP3
  • GS
  • PPP1R46
  • RATAPC
  • APC1
  • APC, WNT signaling pathway regulator
  • adenomatous polyposis coli
  • adenomatous polyposis coli protein, putative
  • adenomatosis polyposis coli
  • adenomatous polyposis coli L homeolog
  • APC
  • apc
  • Smp_139190
  • Apc
  • apc.L
Epitope
AA 2790-2843
28
21
19
18
14
9
9
5
5
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
170
99
71
10
7
6
5
4
2
2
2
1
Host
Rabbit
156
34
13
2
1
Clonality
Polyclonal
Conjugate
Un-conjugated
10
10
7
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
142
100
60
49
45
28
25
20
14
4
4
2
1
1
1
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Catalog No. ABIN702550
$ 306.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN1492008 IHC IHC (p) Rabbit IgG C-Term Log in to see Polyclonal 0
7 ABIN1803997 IHC IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal 0
7 ABIN265313 EIA IF IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN3071937 IHC (p) IP Rabbit C-Term Log in to see Polyclonal 0
4 ABIN2878980 ELISA IHC IHC (p) WB Rabbit IgG AA 2794-2843 Log in to see Polyclonal 0
4 ABIN2852374 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal 0
4 ABIN271993 IHC (p) WB Rabbit Log in to see Polyclonal 0
4 ABIN5693482 IHC (p) ELISA WB Rabbit IgG AA 2794-2843 Log in to see Polyclonal 0
4 ABIN5960388 ELISA IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2891311 IF IHC IHC (p) WB Rabbit Gln2829 Log in to see Polyclonal 0
1 ABIN702559 IHC (p) HRP Rabbit IgG AA 2790-2843 Log in to see Polyclonal 0
1 ABIN702552 IHC (p) Biotin Rabbit IgG AA 2790-2843 Log in to see Polyclonal 0
1 ABIN1893368 IF IHC IHC (p) Rabbit IgG AA 1-50 Log in to see Polyclonal 0
1 ABIN1893367 IF IHC IHC (p) IP Rabbit IgG AA 1-50 Log in to see Polyclonal 0

General

Antigen Adenomatous Polyposis Coli (APC) Antibodies
Epitope AA 2790-2843
(28), (21), (19), (18), (14), (9), (9), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(170), (99), (71), (10), (7), (6), (5), (4), (2), (2), (2), (1)
Host Rabbit
(156), (34), (13), (2), (1)
Clonality
Polyclonal
Conjugate Un-conjugated
(10), (10), (7), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(142), (100), (60), (49), (45), (28), (25), (20), (14), (4), (4), (2), (1), (1), (1)
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Product details

Target Details Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human APC
Isotype IgG

Target Details

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Antigen
Alternative Name Adenomatous Polyposis Coli (APC Antibody Abstract)
Background

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

Subcellular location: Cytoplasm

Synonyms: GS, DP2, DP3, BTPS2, DP2.5, PPP1R46, Adenomatous polyposis coli protein, Protein APC, Deleted in polyposis 2.5, APC

Gene ID 324
UniProt P25054
Pathways WNT Signaling, Stem Cell Maintenance, Cell-Cell Junction Organization

Application Details

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Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product details Target Details Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Adenomatous Polyposis Coli (APC) (AA 2790-2843) antibody (ABIN702550) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-APC/Adenomato...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Adenomatous Polyposis Coli (APC) (AA 2790-2843) antibody (ABIN702550) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-APC/Adenomato...