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|Antigen||Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Antibodies|
|Epitope||AA 6-23 Alternatives|
|Reactivity||Chicken, Dog (Canine), Frog, Human, Mouse (Murine), Orang-Utan (Pongo abelii), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio) Alternatives|
|Conjugate||This CAMK2A antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
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Product Details anti-CAMK2A AntibodyTarget Details CAMK2A Application Details Handling Images
|Specificity||This antibody is directed against human CaM Kinase II protein.|
Species reactivity (expected):Mouse, Rat, Canine, Orangutan, Zebrafish, Chicken, Porcine, Rabbit, Frog.
Species reactivity (tested):Human.
|Characteristics||Concentration: 1.57 mg/mL (by UV absorbance at 280 nm)|
|Immunogen||Synthetic peptide corresponding to amino acids 6-23 of Human CaM Kinase II protein|
Target Details CAMK2AProduct Details anti-CAMK2A Antibody Application Details Handling Images back to top
|Alternative Name||CAMK2A (CAMK2A Antibody Abstract)|
|Background||CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II alpha chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release. CaM Kinase II autophosphorylates itself at Thr-286 which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaM Kinase II is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. This kinase is expressed in brain tissue. Alternative splicing occurs for this gene product.Synonyms: CAMKA, CaM kinase II subunit alpha, CaM-kinase II alpha chain, CaMK-II subunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KIAA0968|
|Pathways||WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction|
Application DetailsProduct Details anti-CAMK2A Antibody Target Details CAMK2A Handling Images back to top
ELISA: 1/4,000 - 1/20,000. Western Blot: 1/1,000 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CAMK2A Antibody Target Details CAMK2A Application Details Images back to top
|Buffer||0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azi|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|