anti-Mouse (Murine) CAMK2D antibody for ELISA

Recommended CAMK2D Antibody (supplied by: Log in to see )

Antigen
Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) Antibodies
  • camk2
  • camkd
  • camkII
  • CAMKD
  • CAMK1
  • Camk2
  • Camki
  • RATCAMKI
  • 2810011D23Rik
  • 8030469K03Rik
  • [d]-CaMKII
  • mKIAA4163
  • calcium/calmodulin dependent protein kinase II delta
  • calcium/calmodulin dependent protein kinase (CaM kinase) II delta
  • calcium/calmodulin dependent protein kinase (CaM kinase) II delta S homeolog
  • calcium/calmodulin-dependent protein kinase II delta
  • calcium/calmodulin-dependent protein kinase II, delta
  • CAMK2D
  • camk2d
  • camk2d.S
  • Camk2d
Reactivity
Human, Mouse (Murine), Rat (Rattus)
77
44
30
9
5
4
4
3
2
2
2
2
1
1
Host
Rabbit
83
10
Clonality
Polyclonal
Conjugate
This CAMK2D antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
79
45
44
13
13
13
2
2
1
1
Supplier
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Catalog No. ABIN6260430
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1963816 IHC ELISA WB APC Rabbit IgG AA 221-250 Log in to see Polyclonal 0
1 ABIN1966451 IHC ELISA WB Biotin Rabbit IgG AA 221-250 Log in to see Polyclonal 0
1 ABIN1974836 IHC ELISA WB PE Rabbit IgG AA 221-250 Log in to see Polyclonal 0
1 ABIN1972385 IHC ELISA WB HRP Rabbit IgG AA 221-250 Log in to see Polyclonal 0
1 ABIN1961439 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 221-250 Log in to see Polyclonal 0
1 ABIN1970258 IHC ELISA WB FITC Rabbit IgG AA 221-250 Log in to see Polyclonal 0
1 ABIN2617866 ELISA IHC WB Rabbit IgG AA 221-250 Log in to see Polyclonal 0
1 ABIN6103837 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN2902047 ELISA IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1083641 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5896054 ELISA WB Rabbit IgG pThr287 Log in to see Polyclonal 0
1 ABIN6104932 ELISA IHC WB Rabbit IgG pThr287 Log in to see Polyclonal 0

General

Antigen Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(77), (44), (30), (9), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(83), (10)
Clonality
Polyclonal
Conjugate This CAMK2D antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(79), (45), (44), (13), (13), (13), (2), (2), (1), (1)
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Product Details anti-CAMK2D Antibody

Target Details CAMK2D Application Details Handling Images
Specificity CAMK2D Antibody detects endogenous levels of total CAMK2D
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human CAMK2D
Isotype IgG
Plasmids, Primers & others

Target Details CAMK2D

Product Details anti-CAMK2D Antibody Application Details Handling Images back to top
Antigen
Alternative Name CAMK2D (CAMK2D Antibody Abstract)
Background

Description: Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca2+ homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca2+ influx into the myocyte, Ca2+ release from the sarcoplasmic reticulum (SR), SR Ca2+ uptake and Na+ and K+ channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure. Contributes to cardiac decompensation and heart failure by regulating SR Ca2+ release via direct phosphorylation of RYR2 Ca2+ channel on 'Ser-2808'. In the nucleus, phosphorylates the MEF2 repressor HDAC4, promoting its nuclear export and binding to 14-3-3 protein, and expression of MEF2 and genes involved in the hypertrophic program. Is essential for left ventricular remodeling responses to myocardial infarction. In pathological myocardial remodeling acts downstream of the beta adrenergic receptor signaling cascade to regulate key proteins involved in ECC. Regulates Ca2+ influx to myocytes by binding and phosphorylating the L-type Ca2+ channel subunit beta-2 CACNB2. In addition to Ca2+ channels, can target and regulate the cardiac sarcolemmal Na+ channel Nav1.5/SCN5A and the K+ channel Kv4.3/KCND3, which contribute to arrhythmogenesis in heart failure. Phosphorylates phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2, contributing to the enhancement of SR Ca2+ uptake that may be important in frequency-dependent acceleration of relaxation (FDAR) and maintenance of contractile function during acidosis. May participate in the modulation of skeletal muscle function in response to exercise, by regulating SR Ca2+ transport through phosphorylation of PLN/PLB and triadin, a ryanodine receptor-coupling factor.

Gene: CAMK2D

Molecular Weight 56 kDa
Gene ID 817
UniProt Q13557
Pathways WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration

Application Details

Product Details anti-CAMK2D Antibody Target Details CAMK2D Handling Images back to top
Application Notes WB 1:1000-3000
Restrictions For Research Use only

Handling

Product Details anti-CAMK2D Antibody Target Details CAMK2D Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months