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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN1805140 | IHC (p) WB | Rabbit | AA 448-478 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) Antibodies |
Epitope | C-Term Alternatives |
Reactivity | Human, Primate Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This CAMK2D antibody is un-conjugated Alternatives |
Application |
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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3 references available |
Supplier | Log in to see |
Product Details anti-CAMK2D AntibodyTarget Details CAMK2D Application Details Handling References for anti-CAMK2D antibody (ABIN359403) Images |
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Specificity | This antibody detects CAMK2D at C-term. |
Purification | Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CAMK2 delta. |
Isotype | Ig Fraction |
Target Details CAMK2DProduct Details anti-CAMK2D Antibody Application Details Handling References for anti-CAMK2D antibody (ABIN359403) Images back to top |
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Antigen | |
Alternative Name | CAMK2D (CAMK2D Antibody Abstract) |
Background | CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.Synonyms: CAMKD, CaM kinase II subunit delta, CaM-kinase II delta chain, CaMK-II subunit delta, Calcium/calmodulin-dependent protein kinase type II delta chain |
Molecular Weight | 56297 Da |
Gene ID | 817, 9606 |
UniProt | Q13557 |
Pathways | WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration |
Application DetailsProduct Details anti-CAMK2D Antibody Target Details CAMK2D Handling References for anti-CAMK2D antibody (ABIN359403) Images back to top |
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Application Notes |
ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
Restrictions | For Research Use only |
HandlingProduct Details anti-CAMK2D Antibody Target Details CAMK2D Application Details References for anti-CAMK2D antibody (ABIN359403) Images back to top |
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Format | Liquid |
Concentration | 0.25 mg/mL |
Buffer | PBS with 0.09 % (W/V) sodium azide |
Preservative | Sodium azide |
Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freezing and thawing. |
Storage | 4 °C/-20 °C |
Storage Comment | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. |
References for anti-CAMK2D antibody (ABIN359403)Product Details anti-CAMK2D Antibody Target Details CAMK2D Application Details Handling Images back to top |
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Background publications |
Boussen, Kochbati, Besbes, Dhiab, Makhlouf, Jerbi, Gamoudi, Benna, Rahal, Maalej, Ben Ayed: "[Male secondary breast cancer after treatment for Hodgkin's disease. Case report and review of the literature]." in: Cancer radiothérapie : journal de la Société française de radiothérapie oncologique, Vol. 4, Issue 6, pp. 465-8, 2001 Hoch, Meyer, Hetzer, Krause, Karczewski: "Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium." in: Circulation research, Vol. 84, Issue 6, pp. 713-21, 1999 Tombes, Krystal: "Identification of novel human tumor cell-specific CaMK-II variants." in: Biochimica et biophysica acta, Vol. 1355, Issue 3, pp. 281-92, 1997 |
ImagesProduct Details anti-CAMK2D Antibody Target Details CAMK2D Application Details Handling References for anti-CAMK2D antibody (ABIN359403) back to top |
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Supplier Images |