Browse our anti-CTNNB1 (CTNNB1) Antibodies

Horse (Equine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. temporal expression of CTNNB1 mRNA during dermal wound repair in the horse

Mouse (Murine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. In fibrocystin/polyductin (show PKHD1 Antibodies) complex-defective cholangiocytes, beta-catenin and IL-1beta (show IL1B Antibodies) are responsible for signal transducer and activator of transcription 3 (show STAT3 Antibodies)-dependent secretion of CXCL10 (show CXCL10 Antibodies)

2. Data illustrates a cooperative effect of the direct oncogenic signaling of mutant beta-catenin and MET in hepatocytes with hepatic tumor-promoting stroma induced by beta-catenin deficiency

3. Data show that beta-catenin can physically interact with Polycomb (show CBX2 Antibodies) Repressive Complex 2 (PRC2) components in the cranial mesenchyme (CM).

4. Study identified FXR (show NR1H4 Antibodies)/beta-catenin interaction whose modulation through beta-catenin suppression promotes FXR (show NR1H4 Antibodies) activation and decreases hepatic bile acids, which may provide unique therapeutic opportunities in cholestatic liver diseases

5. In this study, we found that the wnt (show WNT2 Antibodies) co-receptor Lrp6 (show LRP6 Antibodies) was a potent positive regulator of beta-catenin signaling in TDI-induced asthma models, both in vivo and in vitro. Additionally, for the first time, we demonstrated that RAGE (show AGER Antibodies) could mediate phosphorylation of Lrp6 (show LRP6 Antibodies), suggesting a functional cross talk between RAGE (show AGER Antibodies) and the canonical wnt (show WNT2 Antibodies)/beta-catenin signaling pathway involved in mediating beta-catenin activation.

6. These data indicate that SMAD3 (show SMAD3 Antibodies)- and beta-catenin-dependent induction occurs in the taurine transporter knockout mouse

7. beta-catenin in osterix (show SP7 Antibodies)-expressing cells is required for postnatal osteoblast differentiation, osteoblast proliferation, and bone resorption, and is essential for the anabolic actions of parathyroid hormone (show PTH Antibodies) in bone.

8. the beta-catenin C-terminus indirectly represses p53 (show TP53 Antibodies), and this function is essential for embryogenesis.

9. aberrant expression of AF1q (show MLLT11 Antibodies) may activate Wnt (show WNT2 Antibodies)/beta-catenin signaling and result in podocyte injury.

10. this study suggested that stabilized beta-catenin ameliorated some Autoimmune lymphoproliferative syndrome-like symptoms of lpr/lpr (show FAS Antibodies) mice by potentiating Fas (show FAS Antibodies)-independent signal-mediated T cell apoptosis

Zebrafish Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. The results demonstrate that the argon plasma jet (show FBXL15 Antibodies) has no adverse effects on fin regeneration and embryogenesis in zebrafish, and does not interrupt the (Wnt (show WNT2 Antibodies))/beta-Catenin-signaling pathways.

2. The expression of c-kit and beta-catenin suggests that erythropoietin (show EPO Antibodies) may exert a role in regeneration reducing the extent of tubular damage from the outset after gentamicin administration.

3. Net1-regulated beta-catenin activation plays a crucial role in the dorsal axis formation during zebrafish development.

4. Wnt (show WNT2 Antibodies)/beta-catenin signaling induces expression of col12a1a/b and deposition of Collagen XII, which is necessary for axons to actively navigate the non-neural lesion site environment.

5. Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.

6. Nuclear beta-catenin is an indication of an activated Wnt (show WNT2 Antibodies) pathway, therefore suggesting a possible role for Wnt (show WNT2 Antibodies) signalling during zebrafish tooth development and replacement.

7. Findings suggest that microRNA 19b (miR (show MYLIP Antibodies)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.

8. Custos binds to beta-catenin in a Wnt (show WNT2 Antibodies) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.

9. The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.

10. The Wnt (show WNT2 Antibodies)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)

Xenopus laevis Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. We identified the amphibian leap2 (show LEAP2 Antibodies) gene which is highly related to its mammalian orthologues at both structural and sequence levels. The gene is expressed in the embryo mostly in the endoderm-derived tissues. Accordingly it is induced in pluripotent animal cap cells by FGF, activin (show Actbeta Antibodies) or a combination of vegT/beta-catenin.

2. Together, these results indicate that capsaicin inhibits the patterning of the dorso-ventral and anterior-posterior body axes of embryo by repressing PP2A (show PPP2R2B Antibodies) and thereby down-regulating the Wnt (show WNT2 Antibodies)/beta-catenin signaling.

3. maternal Wnt (show WNT2 Antibodies)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression

4. Custos binds to beta-catenin in a Wnt (show WNT2 Antibodies) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.

5. Wnt (show WNT2 Antibodies) signalling can benefit from nucleo-cytoplasmic shuttling of APC (show APC Antibodies), Axin (show AXIN1 Antibodies) and GSK3, although they are in general beta-catenin antagonising proteins.

6. Phosphoinositide 3-kinase and Rac (show AKT1 Antibodies) polarization depend specifically on the N-cadherin (show CDH2 Antibodies)-p120 catenin (show CTNND1 Antibodies) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (show CDH2 Antibodies)-beta-catenin complex.

7. HERG (show KCNH2 Antibodies) channel activity is stimulated by beta-catenin

8. Zic3 (show ZIC3 Antibodies) can suppress Wnt (show WNT2 Antibodies)/beta-catenin signaling and control development of the notochord and Spemann's organizer.

9. Notch initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3

10. The tyrosine kinase receptor (show KDR Antibodies), PTK7 (show PTK7 Antibodies), is implicated in beta-catenin-dependent developmental processes.

Human Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. High CTNNB1 expression is associated with the recurrece of Adamantinomatous Craniopharyngiomas.

2. High CTNNB1 expression is associated with uterine fibroids.

3. The nucleus and/or cytoplasm expression of beta-catenin was associated with tumor progression and correlated overall survival of patients with ovarian cancer (OC). beta-catenin may be a possible potential prognostic biomarker for the patients with OC. [review]

4. In the two wild type (WT) cases, two novel alterations were detected: a complex deletion of APC (show APC Antibodies) and a pathogenic mutation of LAMTOR2 (show LAMTOR2 Antibodies). Focusing on WT DT subtype, deep sequencing of CTNNB1, APC (show APC Antibodies) and LAMTOR2 (show LAMTOR2 Antibodies) was conducted on a retrospective series of 11 WT DT using a targeted approach

5. DLX1 interacted with beta-catenin and enhanced the interaction between beta-catenin and TCF4 (show TCF4 Antibodies) T-cell factor

6. Nuclear beta-catenin immunoreactivity with appropriate criteria may be helpful to distinguish basal cell adenocarcinoma (BCAC) from histologically similar tumors. However, a minor subset of adenoid cystic carcinoma (ACC (show ACACA Antibodies)) with nuclear beta-catenin expression require careful diagnosis.

7. High CTNNB1 expression is associated with metastasis in cholangiocarcinoma.

8. beta;-catenin directly interacts with the Cx43 (show GJA1 Antibodies) carboxyl-terminal domain.

9. This study showed that beta-catenin expression was the most evident in the nucleus rather than in cytoplasm.

10. Nuclear beta-catenin accumulation in non-mitotic glioblastoma cells is due to a feed forward mechanism between DOCK4 (show DOCK4 Antibodies) and beta-catenin.

Pig (Porcine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. Results highlight a potential role for the beta-catenin/Wnt (show WNT2 Antibodies) and Notch (show NOTCH1 Antibodies) signalling pathways during the infection of crypt cells by L. intracellularis.

2. Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.

3. beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.

4. Wnt3a (show WNT3A Antibodies) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.

5. beta-catenin controls myocardin (show MYOCD Antibodies)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes

6. beta-Catenin plays a critical role in mediating TGF-beta1 (show TGFB1 Antibodies)-induced myofibroblast differentiation in aortic valve interstitial cells.

7. scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin

8. Data show that Wnt3a (show WNT3A Antibodies) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (show WNT2 Antibodies)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.

9. TNF-alpha (show TNF Antibodies) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.

Cow (Bovine) Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. Bovine herpesvirus 1 transiently increased beta-catenin protein levels in bovine kidney cells, but not in rabbit skin cells.

2. These results demonstrate that activation of AKT (show AKT1 Antibodies) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.

3. beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.

4. These data demonstrate for the first time that FSH (show BRD2 Antibodies) regulates CTNNB1 protein and WNT2 (show WNT2 Antibodies) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (show WNT2 Antibodies) signaling in ovarian steroidogenesis and follicular growth of cattle.

5. These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.

6. that beta-catenin is a plasma membrane-associated protein (show PDZK1IP1 Antibodies) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.

7. This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.

8. TGF-beta3 (show TGFB3 Antibodies) induces the chondrogenic differentiation of pericytes by inducing Wnt (show WNT2 Antibodies)/beta-catenin signaling and T-cell factor-induced gene transcription.

9. cAMP/PKA regulation of GSK3beta/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.

Rabbit Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) interaction partners

1. Palmatin effect on osteoarthritis is likely mediated via the Wnt (show WNT2 Antibodies)/beta-catenin and Hedgehog (show SHH Antibodies) signaling

2. These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.