anti-Human CTNNB1 antibody for Immunocytochemistry
Recommended CTNNB1 Antibody (supplied by: Log in to see )
- Antigen
-
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
show synonyms for this antigen- Jup
- LOC100217813
- CTNNB1
- CTNNB
- Bfc
- Catnb
- Mesc
- ctnnb
- id:ibd2058
- wu:fb73e10
- wu:fi81c06
- wu:fk25h01
- ctnnb1
- CHBCAT
- MRD19
- armadillo
- beta-catenin
- catenin beta 1
- catenin (cadherin associated protein), beta 1
- catenin (cadherin-associated protein), beta 1
- catenin beta 1 S homeolog
- catenin beta 1 L homeolog
- CTNNB1
- Ctnnb1
- ctnnb1
- ctnnb1.S
- ctnnb1.L
- Reactivity
-
Human
Alternatives - Host
-
Mouse
Alternatives - Clonality
- Conjugate
-
This CTNNB1 antibody is un-conjugated
Alternatives - Application
-
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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Catalog No. ABIN969072
$ 393.80
Plus shipping costs $45.00
Plus shipping costs $45.00
| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 25.960382 | ABIN457419 | ICC FACS IP WB | Mouse | IgG1 | C-Term, AA 441-448 | Log in to see | EM-22 | 3 | ||
| 1 | ABIN3044344 | ICC IHC (fro) IHC (p) WB | Rabbit | IgG | AA 764-781, C-Term | Log in to see | Polyclonal | 3 | ||
| 1 | ABIN5518651 | ICC IHC (fro) IHC (p) WB | Rabbit | IgG | AA 1-19, N-Term | Log in to see | Polyclonal | 3 | ||
| 1 | ABIN1858529 | ICC IHC WB | Rabbit | IgG | AA 439-675 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN2869463 | ELISA FACS ICC IHC WB | Mouse | IgG1 | Log in to see | 4D5 | 3 | |||
| 1 | ABIN574434 | ICC FACS IHC (p) IP WB | Mouse | IgG1 | Log in to see | EM-22 | 0 | |||
| 1 | ABIN364501 | ICC IHC (p) IP WB | Mouse | IgG | AA 758-771, C-Term | Log in to see | 0 | |||
| 1 | ABIN211079 | ICC IP WB | Rabbit | IgG | AA 29-49 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN200357 | ICC IP IHC WB | Mouse | IgG | AA 758-771, C-Term | Log in to see | 0 | |||
| 1 | ABIN600589 | ICC IHC ELISA WB | Mouse | IgG1, kappa | AA 36-44 | Log in to see | 0 | |||
| 1 | ABIN2619644 | ICC IHC (fro) IHC (p) WB | Rabbit | IgG | AA 1-19 | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN3020927 | ICC IP IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN215673 | ICC IP ELISA WB | Mouse | IgG2b | Log in to see | 0 | ||||
| 1 | ABIN215671 | ICC IHC (p) ELISA WB | Mouse | IgG1 | AA 35-50 | Log in to see | 0 | |||
| 1 | ABIN600588 | ICC IHC ELISA WB | Mouse | IgG1, kappa | AA 36-44 | Log in to see | 0 | |||
| 1 | ABIN604612 | ICC ELISA WB | Mouse | IgG1 | Log in to see | 0 | ||||
| 1 | ABIN1962422 | ELISA ICC IF IHC WB | Alkaline Phosphatase (AP) | Rabbit | IgG | AA 653-681 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN1964799 | ELISA ICC IF IHC WB | APC | Rabbit | IgG | AA 653-681 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN1975812 | ELISA ICC IF IHC WB | PE | Rabbit | IgG | AA 653-681 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN2740182 | ICC IF IHC (p) WB | Rabbit | N-Term | Log in to see | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies |
| Reactivity | Human Alternatives |
| Host | Mouse Alternatives |
| Clonality (Clone) | |
| Conjugate | This CTNNB1 antibody is un-conjugated Alternatives |
| Application |
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Alternatives
|
|
3 references available |
| Supplier | Log in to see |
Product Details anti-CTNNB1 AntibodyTarget Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN969072) Images |
|
| Purification | Ascites |
| Immunogen | Purified recombinant fragment of human CTNNB1 expressed in E. Coli. |
| Clone | 4D5 |
| Isotype | IgG1 |
Target Details CTNNB1Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 antibody (ABIN969072) Images back to top |
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| Antigen | |
| Alternative Name | CTNNB1 (CTNNB1 Antibody Abstract) |
| Background | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. |
| Molecular Weight | 85 kDa |
| Gene ID | 1499 |
| HGNC | 1499 |
| Pathways | WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2 |
Application DetailsProduct Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 antibody (ABIN969072) Images back to top |
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| Application Notes | ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 antibody (ABIN969072) Images back to top |
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| Format | Liquid |
| Buffer | Ascitic fluid containing 0.03 % sodium azide. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Storage | 4 °C,-20 °C |
| Storage Comment | 4°C, -20°C for long term storage |
References for anti-CTNNB1 antibody (ABIN969072)Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top |
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| Product cited in: |
Bougatef, Ouerhani, Moussa, Kourda, Coulet, Colas, Lahely, Najjar, Ben Jilani, Benammar-Elgaaied, Soubrier, Marrakchi: "Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer." in: Cancer genetics and cytogenetics, Vol. 187, Issue 1, pp. 12-8, 2008 Guo, Liu, Yang, Zhang, Yao: "Relation among p130Cas, E-cadherin and beta-catenin expression, clinicopathologic significance and prognosis in human hepatocellular carcinoma." in: Hepatobiliary & pancreatic diseases international : HBPD INT, Vol. 7, Issue 5, pp. 490-6, 2008 |
| Background publications |
Rubinfeld, Souza, Albert, Munemitsu, Polakis: "The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin." in: The Journal of biological chemistry, Vol. 270, Issue 10, pp. 5549-55, 1995 |
ImagesProduct Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 antibody (ABIN969072) back to top |
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| Supplier Images |
Figure 1: Flow cytometric analysis of A549 cells using CTNNB1 mouse mAb (green) and n...
Figure 2: Immunofluorescence analysis of A549 (left) and SK-BR-3 (right) cells using ...
Figure 3: Immunohistochemical analysis of paraffin-embedded human Placenta tissues us...
Figure 4: Western blot analysis using CTNNB1 mouse mAb against CTNNB1-hIgGFc transfec...
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