Get this product for free
Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
---|---|---|---|---|---|---|---|---|---|---|
16.736145 | ABIN5693200 | IHC WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
12.138491 | ABIN4901562 | ELISA WB | Rabbit | IgG | AA 11-60 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN636047 | IHC WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
12.138491 | ABIN5651189 | IHC WB | APC | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651190 | IHC WB | Atto 390 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651192 | IHC WB | Atto 565 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651191 | IHC WB | Atto 488 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651194 | IHC WB | Atto 633 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651203 | IHC WB | PerCP | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651199 | IHC WB | Biotin | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651193 | IHC WB | Atto 594 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651196 | IHC WB | Atto 680 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651198 | IHC WB | Alkaline Phosphatase (AP) | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651195 | IHC WB | Atto 655 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651200 | IHC WB | FITC | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651202 | IHC WB | PE-Atto 594 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651201 | IHC WB | HRP | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651205 | IHC WB | Streptavidin | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651204 | IHC WB | PE | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 | ||
12.138491 | ABIN5651197 | IHC WB | Atto 700 | Rabbit | AA 100-200 | Log in to see | Polyclonal | 0 |
General |
|
---|---|
Antigen | Frizzled Family Receptor 4 (FZD4) Antibodies |
Epitope | Middle Region Alternatives |
Reactivity | Cow (Bovine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This FZD4 antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
|
![]() |
4 references available |
Supplier | Log in to see |
Product Details anti-FZD4 AntibodyTarget Details FZD4 Application Details Handling References for anti-FZD4 antibody (ABIN2776715) Images |
|
Blocking Peptide | Blocking peptide for this product available: ABIN977169 |
Sequence | GITSGMWIWS AKTLHTWQKC SNRLVNSGKV KREKRGNGWV KPGKGSETVV |
Predicted Reactivity | Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100% |
Characteristics | This is a rabbit polyclonal antibody against FZD4. It was validated on Western Blot using a cell lysate as a positive control. |
Purification | Affinity Purified |
Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human FZD4 |
Plasmids, Primers & others | |
Target Details FZD4Product Details anti-FZD4 Antibody Application Details Handling References for anti-FZD4 antibody (ABIN2776715) Images back to top |
|
Antigen | |
Alternative Name | FZD4 (FZD4 Antibody Abstract) |
Background |
FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Alias Symbols: EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, CD344 Protein Interaction Partner: UBC, NDP, ZNRF3, BAG6, MAGI3, DLG2, DLG4, DVL2, DLG1, ARRB2, Protein Size: 537 |
Molecular Weight | 60 kDa |
Gene ID | 8322 |
NCBI Accession | NM_012193, NP_036325 |
UniProt | Q9ULV1 |
Pathways | WNT Signaling, Hormone Transport, Sensory Perception of Sound |
Application DetailsProduct Details anti-FZD4 Antibody Target Details FZD4 Handling References for anti-FZD4 antibody (ABIN2776715) Images back to top |
|
Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
Comment |
Antigen size: 537 AA |
Restrictions | For Research Use only |
HandlingProduct Details anti-FZD4 Antibody Target Details FZD4 Application Details References for anti-FZD4 antibody (ABIN2776715) Images back to top |
|
Format | Liquid |
Concentration | Lot specific |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-FZD4 antibody (ABIN2776715)Product Details anti-FZD4 Antibody Target Details FZD4 Application Details Handling Images back to top |
|
Product cited in: |
Wang, Pawlak, Johnson, Belknap, Eades, Stack, Cousin, Black: "Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae." in: PLoS ONE, Vol. 8, Issue 2, pp. e56025, 2013 McIver, Stanger, Santarelli, Roman, Nixon, McLaughlin: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, 2012 Gonzalez, Fernandez-Martos, Gonzalez-Fernandez, Arenas, Rodriguez: "Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats." in: PLoS ONE, Vol. 7, Issue 12, pp. e50793, 2012 |
Background publications |
Dufourcq, Leroux, Ezan, Descamps, Lamazière, Costet, Basoni, Moreau, Deutsch, Couffinhal, Duplàa: "Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation." in: The American journal of pathology, Vol. 172, Issue 1, pp. 37-49, 2008 |
ImagesProduct Details anti-FZD4 Antibody Target Details FZD4 Application Details Handling References for anti-FZD4 antibody (ABIN2776715) back to top |
|
Supplier Images |
|