anti-Cow (Bovine) FZD7 antibody for Immunohistochemistry
Recommended FZD7 Antibody (supplied by: Log in to see )
- Antigen
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Frizzled Family Receptor 7 (FZD7) Antibodies
show synonyms for this antigen- Fz-7
- Xfz7
- frizzled-7
- frizzled7
- frz-7
- frz7
- fz7
- fze3
- FzE3
- fzd7-a
- fzd7-b
- cFz-7
- Fz7
- frizzled class receptor 7
- frizzled class receptor 7 L homeolog
- cyclin-dependent kinase 15
- FZD7
- fzd7
- fzd7.L
- Cdk15
- Fzd7
- Epitope
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C-Term
Alternatives - Reactivity
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Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Yeast (Saccharomyces cerevisiae)
Alternatives - Host
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Rabbit
Alternatives - Clonality
- Conjugate
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This FZD7 antibody is un-conjugated
Alternatives - Application
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Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 8.549343 | ABIN337331 | ELISA IHC IHC (p) WB | Goat | AA 559-572 | Log in to see | Polyclonal | 0 | |||
| 8.549343 | ABIN1048627 | IHC IHC (p) | Rabbit | N-Term | Log in to see | Polyclonal | 0 | |||
| 8.549343 | ABIN1048628 | IHC IHC (p) | Rabbit | N-Term | Log in to see | Polyclonal | 0 | |||
| 8.549343 | ABIN213489 | ELISA IHC IHC (p) | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
| 8.549343 | ABIN2469409 | IHC ELISA | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
| 1 | ABIN216661 | IHC IHC (p) WB | Rabbit | IgG | C-Term | Log in to see | Polyclonal | 0 | ||
| 1 | ABIN4312613 | IHC IHC (p) | Rabbit | C-Term | Log in to see | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Frizzled Family Receptor 7 (FZD7) Antibodies |
| Epitope | C-Term Alternatives |
| Reactivity | Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Yeast (Saccharomyces cerevisiae) Alternatives |
| Host | Rabbit Alternatives |
| Clonality | |
| Conjugate | This FZD7 antibody is un-conjugated Alternatives |
| Application |
Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
|
|
6 references available |
| Supplier | Log in to see |
Product Details anti-FZD7 AntibodyTarget Details FZD7 Application Details Handling References for anti-FZD7 antibody (ABIN2776708) Images |
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| Blocking Peptide | Blocking peptide for this product available: ABIN977173 |
| Sequence | PDFTVFMIKY LMTMIVGITT GFWIWSGKTL QSWRRFYHRL SHSSKGETAV |
| Predicted Reactivity | Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82% |
| Characteristics | This is a rabbit polyclonal antibody against FZD7. It was validated on Western Blot and immunohistochemistry. |
| Purification | Affinity Purified |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human FZD7 |
| Plasmids, Primers & others | |
Target Details FZD7Product Details anti-FZD7 Antibody Application Details Handling References for anti-FZD7 antibody (ABIN2776708) Images back to top |
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| Antigen | |
| Alternative Name | FZD7 (FZD7 Antibody Abstract) |
| Background |
FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Alias Symbols: FzE3 Protein Interaction Partner: UBC, UBQLN4, MAGI3, UBQLN1, DLG2, DLG4, DLG1, Protein Size: 574 |
| Molecular Weight | 63 kDa |
| Gene ID | 8324 |
| NCBI Accession | NM_003507, NP_003498 |
| UniProt | O75084 |
| Pathways | WNT Signaling, Stem Cell Maintenance |
Application DetailsProduct Details anti-FZD7 Antibody Target Details FZD7 Handling References for anti-FZD7 antibody (ABIN2776708) Images back to top |
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| Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
| Comment |
Antigen size: 574 AA |
| Restrictions | For Research Use only |
HandlingProduct Details anti-FZD7 Antibody Target Details FZD7 Application Details References for anti-FZD7 antibody (ABIN2776708) Images back to top |
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| Format | Liquid |
| Concentration | Lot specific |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Handling Advice | Avoid repeated freeze-thaw cycles. |
| Storage | -20 °C |
| Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-FZD7 antibody (ABIN2776708)Product Details anti-FZD7 Antibody Target Details FZD7 Application Details Handling Images back to top |
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| Product cited in: |
McIver, Stanger, Santarelli, Roman, Nixon, McLaughlin: "A unique combination of male germ cell miRNAs coordinates gonocyte differentiation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35553, 2012 Schmuck, Warneke, Behrens, Simon, Weichert, Röcken: "Genotypic and phenotypic characterization of side population of gastric cancer cell lines." in: The American journal of pathology, Vol. 178, Issue 4, pp. 1792-804, 2011 Gökmen-Polar, Toroni, Hocevar, Badve, Zhao, Shen, Bruckheimer, Kinch, Miller: "Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer." in: Breast cancer research and treatment, Vol. 127, Issue 2, pp. 375-84, 2011 Ohba, Lanigan, Roessler: "Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 18, Issue 12, pp. 1620-9, 2010 Ueno, Hiura, Suehiro, Hazama, Hirata, Oka, Imai, Dahiya, Hinoda: "Frizzled-7 as a potential therapeutic target in colorectal cancer." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 7, pp. 697-705, 2008 |
| Background publications |
Vincan, Darcy, Smyth, Thompson, Thomas, Phillips, Ramsay: "Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth." in: Differentiation; research in biological diversity, Vol. 73, Issue 4, pp. 142-53, 2005 |
ImagesProduct Details anti-FZD7 Antibody Target Details FZD7 Application Details Handling References for anti-FZD7 antibody (ABIN2776708) back to top |
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| Supplier Images |
WB Suggested Anti-FZD7 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cel...
Rabbit Anti-FZD7 Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epit...
WB Suggested Anti-FZD7 Antibody Titration: 0.2-1 µg/mL Positive Control... 
Host: Rabbit Target Name: FZD7 Sample Tissue: Human A549 Whole Cell Antibody Di...
Host: Rabbit Target Name: FZD7 Sample Tissue: Human Ovary Tumor Antibody Diluti...
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