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anti-Human SFRP4 Antibodies:
anti-Mouse (Murine) SFRP4 Antibodies:
anti-Rat (Rattus) SFRP4 Antibodies:
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Human Polyclonal SFRP4 Primary Antibody for ELISA, WB - ABIN562837
Bishop, Hennebold, Stouffer: The effects of luteinizing hormone ablation/replacement versus steroid ablation/replacement on gene expression in the primate corpus luteum. in Molecular human reproduction 2009
Show all 3 Pubmed References
Human Polyclonal SFRP4 Primary Antibody for IHC (p), IHC - ABIN451820
Linhart, Lin, Yamada, Moran, Steine, Gokhale, Lo, Cantu, Ehrich, He, Meissner, Jaenisch: Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. in Genes & development 2007
Human Polyclonal SFRP4 Primary Antibody for IHC, IHC (p) - ABIN4353140
Jiang, Li, He, Li, Sheng, Shen, Zhang, Zhu, Chen, Chen, Yang, Gao: Activation of the Wnt pathway through Wnt2 promotes metastasis in pancreatic cancer. in American journal of cancer research 2014
Studied role of Secreted Frizzled-Related Protein 4 (sFRP4) in angiostasis thru nitric oxide-cGMP cell signaling.
Progesterone regulated SFRP4 gene expression plays a role in uterine leiomyoma.
SFRP4 expression is significantly upregulated in human masticatory mucosa during wound healing
SFRP4 is significantly increased in patients with different types of diabetes.
Weak sFRP4 expression appeared to predict aggressive behavior, and was associated with recurrence/progression of GH-secreting pituitary adenomas.
A decreased risk of lung cancer was found for the genotype combination of DKK3 (show DKK3 Antibodies) and sFRP4.
Down-regulation of SFRP4 is associated with recurrence in Endometrioid Adenocarcinoma.
proliferation of IGFBP5 (show IGFBP5 Antibodies)-mutated cancer cells is selectively blocked by IGF-1R (show IGF1R Antibodies) inhibitors
concentrations of serum SFRP4 in T2DM and impaired glucose tolerance subjects were increased and were correlated closely with glycose metabolic disorder, the first-phase of glucose-stimulated insulin (show INS Antibodies) secretion and chronic low-grade inflammation
sFRP4 expression is inversely related to the aggressiveness of pituitary adenomas, and acts as a tumor suppressor.
Upregulation of Wnt (show WNT2 Antibodies) antagonist SFRP4 and adipogenic gene expression following castration, contributes to increased intramuscular fat deposition in the longissimus dorsi muscle.
Results indicate that sFRP4 plays a critical role in bone development and remodeling by regulating osteoblasts and osteoclasts, and that its functional loss prevents age-related bone loss in the trabecular bone. These findings imply that it functions as a potential balancer of the Wnt (show WNT2 Antibodies) signaling pathway by direct influencing bone formation and absorption during skeletal bone development and maintenance through remodeling.
the cross-talk between SFRP4, integrin alpha1beta1, and Notch1 (show NOTCH1 Antibodies) suppresses the cardiac differentiation of P19CL6 cells.
Our study showed that Pyle's disease was caused by a deficiency of sFRP4 and that sFRP4-mediated cross-regulation between Wnt and BMP signaling was critical for achieving proper cortical-bone thickness and stability.
MicroRNA-124 regulates cell specification in the cochlea through modulation of Sfrp4 and Sfrp5 (show SFRP5 Antibodies).
In diet-induced obesity, loss of SFRP4 alters body length and bone mineral density as well as energy expenditure and food intake. However, SFRP4 does not control glucose homeostasis and beta-cell mass in mice.
MG-derived oxidative stress (not CpG demethylation) epigenetically and rapidly derepress sFRP-4 gene expression.
findings suggest that an epigenetic event is critically involved in the pathogenesis of psoriasis, and the downregulation of SFRP4 by CpG island methylation is one possible mechanism contributing to the hyperplasia of epidermis in the disease
extra-follicular modulators Bmp2 (show BMP2 Antibodies), Dkk1 (show DKK1 Antibodies), and Sfrp4 increase in early anagen.
studies indicate that mutations neither in sFRP1 (show SFRP1 Antibodies) nor in sFRP4 are a common cause of craniotubular hyperostoses
Data suggest that Sfrp4 does not contribute to the long-term regulation of serum phosphate levels in mice.
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.
secreted frizzled-related protein 4
, secreted frizzled-related protein 4-like
, frizzled protein, human endometrium
, secreted frizzled-related protein 4; secreted frizzled-related protein 4
, secreted frizzled-relatedprotein 4
, frizzled-related protein 4
, secreted frizzled-related sequence protein 4
, DDC-4 protein
, frizzled related protein
, frizzled-related protein