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|Antigen||Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) Antibodies|
|Epitope||AA 45-74, N-Term Alternatives|
|Conjugate||This WNT1 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|2 references available|
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Product Details anti-WNT1 AntibodyTarget Details WNT1 Application Details Handling References for anti-WNT1 antibody (ABIN3042350) Images
|Purpose||Rabbit IgG polyclonal antibody for Proto-oncogene Wnt-1(WNT1) detection. Tested with WB in Human.|
|Sequence||NLLTDSKSLQ LVLEPSLQLL SRKQRRLIRQ|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Proto-oncogene Wnt-1(WNT1) detection. Tested with WB in Human.
Gene Name: wingless-type MMTV integration site family, member 1
Protein Name: Proto-oncogene Wnt-1
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the N-terminus of human Wnt1 (45-74aa NLLTDSKSLQLVLEPSLQLLSRKQRRLIRQ), identical to the related mouse and rat sequences.|
|Plasmids, Primers & others|
Target Details WNT1Product Details anti-WNT1 Antibody Application Details Handling References for anti-WNT1 antibody (ABIN3042350) Images back to top
|Alternative Name||WNT1 (WNT1 Antibody Abstract)|
Wingless-type MMIV integration site family, member 1 is a protein that in humans is encoded by the WNT1 gene. This gene is a member of the WNT gene family. The gene was assigned to human chromosome 12q13.12. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. The Wnt1 protein functions in the induction of the mesencephalon and cerebellum. However, the gene mutations might not have a significant role in Joubert syndrome.
Synonyms: BMND16 antibody|INT1 antibody|OI15 antibody|oncogene Int1 antibody|Proto oncogene protein Wnt 1 antibody|Proto-oncogene Int-1 homolog antibody|Proto-oncogene Wnt-1 antibody|Wingless type MMTV integration site family member 1 antibody|wingless-type MMTV integration site family, member 1 (oncogene INT1) antibody|Wnt 1 antibody|wnt1 antibody|WNT1_HUMAN antibody
|Pathways||WNT Signaling, Dopaminergic Neurogenesis|
Application DetailsProduct Details anti-WNT1 Antibody Target Details WNT1 Handling References for anti-WNT1 antibody (ABIN3042350) Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Wnt1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-WNT1 Antibody Target Details WNT1 Application Details References for anti-WNT1 antibody (ABIN3042350) Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-WNT1 antibody (ABIN3042350)Product Details anti-WNT1 Antibody Target Details WNT1 Application Details Handling Images back to top
|Product cited in:||
Mi, Li, Zhang, Zhao, Peng, Yang, Zheng: "MicroRNA-139-5p regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 93, Issue 1, pp. 8-15, 2015
Dong, Duan, Han, Zhang, Wu: "Suppression of wingless-type MMTV integration site family, member 1 expression by small interfering RNA inhibits U251 glioma cell growth in vitro." in: Oncology letters, Vol. 9, Issue 1, pp. 81-85, 2014
ImagesProduct Details anti-WNT1 Antibody Target Details WNT1 Application Details Handling References for anti-WNT1 antibody (ABIN3042350) back to top