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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN4366161 | ELISA ICC IF IHC IHC (p) WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN1030803 | IHC ELISA WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN2387204 | IF IHC ELISA WB | Rabbit | IgG | C-Term | Log in to see | Polyclonal | 0 | ||
1 | ABIN1585510 | IHC ELISA WB | Rabbit | Log in to see | Polyclonal | 0 | ||||
1 | ABIN1886971 | IHC ELISA WB | Rabbit | C-Term | Log in to see | Polyclonal | 0 | |||
1 | ABIN1872350 | ICC IHC (fro) IHC (p) ELISA WB | Rabbit | IgG | Log in to see | Polyclonal | 0 |
General |
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Antigen | Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A) Antibodies |
Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This WNT10A antibody is un-conjugated Alternatives |
Application |
ELISA, Western Blotting (WB)
Alternatives
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4 references available |
Supplier | Log in to see |
Product Details anti-WNT10A AntibodyTarget Details WNT10A Application Details Handling References for anti-WNT10A antibody (ABIN1003487) Images |
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Blocking Peptide | Blocking peptide for this product available: ABIN1004505 |
Purification | Affinity chromatography purified via peptide column. |
Immunogen | Wnt-10a antibody was raised in rabbits against a 14 amino acid peptide from near the carboxy terminus of human Wnt10a. |
Isotype | IgG |
Target Details WNT10AProduct Details anti-WNT10A Antibody Application Details Handling References for anti-WNT10A antibody (ABIN1003487) Images back to top |
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Antigen | |
Alternative Name | Wnt10a (WNT10A Antibody Abstract) |
Background | Wnt-10a is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Elevated levels of Wnt-10a have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia and it has been suggested that uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes these malignancies. Recently, a mutation in Wnt-10a was found to be associated with odonto-onycho-dermal dysplasia, an autosomal recessive ectodermal dysplasia. Despite the high homology of Wnt-10a to Wnt-10b, this Wnt-10a antibody will not cross-react with Wnt-10b. |
Pathways | WNT Signaling |
Application DetailsProduct Details anti-WNT10A Antibody Target Details WNT10A Handling References for anti-WNT10A antibody (ABIN1003487) Images back to top |
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Application Notes | Wnt10a antibody can be used for detection of Wnt10a by Western blot at 1 – 2 µg/ml. (Optimal dilution should be determined by user). Antibody can also be used for ELISA and might be suited for other applications not tested so far. |
Restrictions | For Research Use only |
HandlingProduct Details anti-WNT10A Antibody Target Details WNT10A Application Details References for anti-WNT10A antibody (ABIN1003487) Images back to top |
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Format | Liquid |
Buffer | Antibody is supplied in PBS containing 0.02% sodium azide. |
Preservative | Sodium azide |
Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. |
Storage | 4 °C |
Expiry Date | 12 months |
References for anti-WNT10A antibody (ABIN1003487)Product Details anti-WNT10A Antibody Target Details WNT10A Application Details Handling Images back to top |
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Product cited in: |
Kirikoshi, Sekihara, Katoh: "WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells." in: Biochemical and biophysical research communications, Vol. 283, Issue 4, pp. 798-805, 2001 Kirikoshi, Inoue, Sekihara, Katoh: "Expression of WNT10A in human cancer." in: International journal of oncology, Vol. 19, Issue 5, pp. 997-1001, 2001 Kelly, Lai, Moon: "Expression of wnt10a in the central nervous system of developing zebrafish." in: Developmental biology, Vol. 158, Issue 1, pp. 113-21, 1993 Nusse, Varmus: "Wnt genes." in: Cell, Vol. 69, Issue 7, pp. 1073-87, 1992 |