anti-Mouse (Murine) WNT5A antibody for Immunofluorescence (Paraffin-embedded Sections)
Recommended WNT5A Antibody (supplied by: Log in to see )
- Antigen
-
Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) Antibodies
show synonyms for this antigen- hWNT5A
- wnt-5A
- wnt5a-B
- WNT5A
- 8030457G12Rik
- Wnt-5a
- Wnt family member 5A
- Wnt family member 5A S homeolog
- wingless-type MMTV integration site family, member 5a
- wingless-type MMTV integration site family, member 5A
- wingless-related MMTV integration site 5A
- Wnt signaling ligand
- WNT5A
- Wnt5a
- wnt5a.S
- wnt5a
- LOC578814
- wnt5
- Epitope
-
AA 330-380
Alternatives - Reactivity
-
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Alternatives - Host
-
Rabbit
Alternatives - Clonality
- Conjugate
-
This WNT5A antibody is un-conjugated
Alternatives - Application
-
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives - Options
- Supplier
- Log in to see
- Supplier Product No.
- Log in to see
Get this product for free
Submit your validation data for this product and get a full refund. I want to validate this product
Available images
Plus shipping costs $45.00
| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ABIN920074 | IF (p) | Alexa Fluor 488 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN920077 | IF (p) | Alexa Fluor 647 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN920073 | IF (p) | Alexa Fluor 350 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN920075 | IF (p) | Alexa Fluor 555 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN675761 | IF (p) | Cy3 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN675762 | IF (p) | Cy5 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN675763 | IF (p) | Cy5.5 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN675764 | IF (p) | Cy7 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN675765 | IF (p) | FITC | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN2807566 | IF (p) | Alexa Fluor 594 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN5012524 | IF (p) | Alexa Fluor 750 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN5012523 | IF (p) | Alexa Fluor 680 | Rabbit | IgG | AA 330-380 | Log in to see | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) Antibodies |
| Epitope | AA 330-380 Alternatives |
| Reactivity | Dog (Canine), Human, Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Rabbit Alternatives |
| Clonality | |
| Conjugate | This WNT5A antibody is un-conjugated Alternatives |
| Application |
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
|
|
2 references available |
| Supplier | Log in to see |
Product Details anti-WNT5A AntibodyTarget Details WNT5A Application Details Handling References for anti-WNT5A antibody (ABIN675758) Images |
|
| Purification | Purified by Protein A. |
| Immunogen | KLH conjugated synthetic peptide derived from human WNT5A |
| Isotype | IgG |
Target Details WNT5AProduct Details anti-WNT5A Antibody Application Details Handling References for anti-WNT5A antibody (ABIN675758) Images back to top |
|
| Antigen | |
| Alternative Name | Wnt5a (WNT5A Antibody Abstract) |
| Background |
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes. Subcellular location: Secreted Synonyms: hWNT5A, Protein Wnt-5a, WNT5A |
| Gene ID | 7474 |
| UniProt | P41221 |
| Pathways | WNT Signaling, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation |
Application DetailsProduct Details anti-WNT5A Antibody Target Details WNT5A Handling References for anti-WNT5A antibody (ABIN675758) Images back to top |
|
| Application Notes |
WB 1:100-1000 IHC-P 1:100-500 IF(IHC-P) 1:50-200 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-WNT5A Antibody Target Details WNT5A Application Details References for anti-WNT5A antibody (ABIN675758) Images back to top |
|
| Format | Liquid |
| Concentration | 1 μg/μL |
| Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
| Storage | -20 °C |
| Storage Comment | Store at -20°C |
| Expiry Date | 12 months |
References for anti-WNT5A antibody (ABIN675758)Product Details anti-WNT5A Antibody Target Details WNT5A Application Details Handling Images back to top |
|
| Product cited in: |
Saha, Aranda, Hayakawa, Bhanja, Atay, Brodin, Li, Asfaha, Liu, Tailor, Zhang, Godwin, Tome, Wang, Guha, Pollard: "Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury." in: Nature communications, Vol. 7, pp. 13096, 2016 Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Dog (Canine)). |
ImagesProduct Details anti-WNT5A Antibody Target Details WNT5A Application Details Handling References for anti-WNT5A antibody (ABIN675758) back to top |
|
| Supplier Images |
Frozen mouse brain sections labeled with Anti-WNT5A Polyclonal Antibody, Unconjugated...
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-WNT5A Pol...
Image kindly submitted by Dr. Magdalena Krol. Formalin-fixed and paraffin embedded ca...
Image kindly provided by Dr. Magdalena Krol. Control tumor cells, tumor cells grown i...
Mouse ovary lysates probed with WNT5A Polyclonal Antibody, unconjugated at 1:300 ove...
Mouse uterus lysates probed with WNT5A Polyclonal Antibody, unconjugated at 1:300 ov...
|
