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2'-5'-Oligoadenylate Synthetase-Like Proteins (OASL)

Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.. Additionally we are shipping OASL Antibodies (40) and OASL Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OASL 8638 Q15646
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Top OASL Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 11 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

OASL Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for 2'-5'-Oligoadenylate Synthetase-Like (OASL) Interaction Partners

Human 2'-5'-Oligoadenylate Synthetase-Like (OASL) interaction partners

  1. OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth.

  2. Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 (show OAS2 Proteins) genes.

  3. these findings show a mechanism by which human OASL contributes to host antiviral responses by enhancing RIG-I (show DDX58 Proteins) activation.

  4. we propose that VSV treatment combined with the selective regulation of genes such as STAT1 (show STAT1 Proteins) and OASL2 will improve therapeutic outcomes for CUG2 (show CENPW Proteins)-overexpressing tumors

  5. variants in LPL (show LCP1 Proteins), OASL and TOMM40 (show TOMM40 Proteins)/APOE (show APOE Proteins)-C1-C2-C4 genes are associated with multiple cardiovascular-related traits

  6. The pronounced difference in gene regulation between the OASL gene agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein.

  7. The expression of OASL and IFIT2 (show IFIT2 Proteins) was significantly higher in SLE patients than in controls.

  8. OASLa, a major isoform of OASL induced in human liver, may mediate anti-HCV activity through two different domains.

  9. interaction with methyl CpG-binding protein 1 (show MBD1 Proteins) was confirmed in vitro and in vivo and was mapped to the ubiquitin-like domain of p59 OASL

  10. Proof that OASL is an antiviral protein that works through a novel mechanism distinct from other OASL proteins in other vertebrate species.

OASL Protein Profile

Protein Summary

Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.

Gene names and symbols associated with OASL

  • 2'-5'-oligoadenylate synthetase-like (OASL)
  • OASLd protein
  • p59 OASL protein
  • p59-OASL protein
  • p59OASL protein
  • TRIP-14 protein
  • TRIP14 protein

Protein level used designations for OASL

2'-5'-oligoadenylate synthetase-like , 59 kDa 2'-5'-oligoadenylate synthetase-like protein-like , 59 kDa 2'-5'-oligoadenylate synthase-like protein-like , 2'-5'-OAS-RP , 2'-5'-OAS-related protein , 2'-5'-oligoadenylate synthase-like protein , 59 kDa 2'-5'-oligoadenylate synthase-like protein , 59 kDa 2'-5'-oligoadenylate synthetase-like protein , TR-interacting protein 14 , thyroid receptor-interacting protein 14

100356242 Oryctolagus cuniculus
100401503 Callithrix jacchus
100455196 Pongo abelii
100483471 Ailuropoda melanoleuca
100587823 Nomascus leucogenys
8638 Homo sapiens
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