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CRISPR-Cas9 System

CRISPR/Cas9 is a genome editing tool that allows scientists to precisely modify DNA sequences within living organisms. It utilizes a bacterial defense system, CRISPR, and the enzyme Cas9 to target specific regions of the genome and make targeted cuts. These cuts can be used to introduce desired genetic changes, such as correcting mutations or disrupting genes of interest. CRISPR/Cas9 has transformed the field of molecular biology, offering unprecedented efficiency, precision, and scalability in genome editing.

The Casilio® System

At antibodies-online, we provide a range of antibodies, proteins, and kits tailored for use with CRISPR/Cas9 technology, empowering researchers and professionals in the life science industry to advance their work in genetic engineering and functional genomics. Addtionally on our second platform genomics-online we offer ready-to-use plasmids and vectors for CRISPR/Cas9. For example Casilio® transgene selection vectors which improve current CRISPR/Cas9 solutions and can be used for epigenetic gene regulation, gene editing or imaging of DNA binding proteins. Learn more about the Casilio® system down below.

Available Antibodies CRISPR/Cas9

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Streptococcus pyogenes
Application WB, IF, IP, ICC
Validations
  • (2)
Cat. No. ABIN4880057
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Staphylococcus aureus
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN6731015
Quantity 100 μg
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Application WB, ELISA, FM
Validations
  • (3)
Cat. No. ABIN5596701
Quantity 100 μg
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Application WB, ELISA, FM
Validations
  • (2)
Cat. No. ABIN5596703
Quantity 100 μg
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Application WB, ELISA, FM
Validations
  • (2)
Cat. No. ABIN5596702
Quantity 100 μg
Datasheet Datasheet
Reactivity Staphylococcus aureus
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7266523
Quantity 100 μL
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Application WB, IF, IP, ChIP
Validations
  • (3)
Cat. No. ABIN5563965
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN5557542
Quantity 100 μL
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Application WB, ELISA, FM
Validations
  • (2)
Cat. No. ABIN6658290
Quantity 100 μg
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Application WB, ELISA, FM
Validations
  • (2)
Cat. No. ABIN6658288
Quantity 100 μg
Datasheet Datasheet

Available Proteins for CRISPR/Cas9

Product
Source
Cat. No.
Quantity
Delivery
Datasheet
Source Escherichia coli (E. coli)
Cat. No. ABIN7447881
Quantity 100 μg
Delivery 5 Days
Datasheet Datasheet

Kits for CRISPR/Cas9

Product
Analytical Method
Cat. No.
Validations
Quantity
Datasheet
Analytical Method Quantitative
Cat. No. ABIN5680040
Validations
Quantity 96 tests
Datasheet Datasheet

References

  1. Ishino, Shinagawa, Makino, Amemura, Nakata: "Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product." in: Journal of bacteriology, Vol. 169, Issue 12, pp. 5429-33, (1988) (PubMed).
  2. Jiang, Doudna: "CRISPR-Cas9 Structures and Mechanisms." in: Annual review of biophysics, Vol. 46, pp. 505-529, (2017) (PubMed).
  3. Doudna, Charpentier: "Genome editing. The new frontier of genome engineering with CRISPR-Cas9." in: Science (New York, N.Y.), Vol. 346, Issue 6213, pp. 1258096, (2014) (PubMed).
  4. Wang, La Russa, Qi: "CRISPR/Cas9 in Genome Editing and Beyond." in: Annual review of biochemistry, Vol. 85, pp. 227-64, (2017) (PubMed).
  5. Zhang, Wen, Guo: "CRISPR/Cas9 for genome editing: progress, implications and challenges." in: Human molecular genetics, Vol. 23, Issue R1, pp. R40-6, (2015) (PubMed).
Julian Pampel
Julian Pampel, BSc
Content Manager at antibodies-online.com

Creative mind of antibodies-online with a keen eye for details. Proficient in the field of life-science with a passion for plant biotechnology and clinical study design. Responsible for illustrated and written content at antibodies-online as well as supervision of the antibodies-online scholarship program.

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