ATM Interactor Proteins (ATMIN)

Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Additionally we are shipping ATM Interactor Antibodies (37) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATMIN 23300 O43313
ATMIN 234776 Q6P9S1
Rat ATMIN ATMIN 315037  
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Top ATM Interactor Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

ATMIN Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for ATM Interactor (ATMIN) Interaction Partners

Human ATM Interactor (ATMIN) interaction partners

  1. WRNIP1 (show WRNIP1 Proteins) connects PCNA (show PCNA Proteins) monoubiquitination with ATMIN/ATM (show ATM Proteins) to activate ATM (show ATM Proteins) signalling in response to replication stress and contribute to the maintenance of genomic stability.

  2. Studies suggest that ATM INteractor (ATMIN) could be an important biomarker in disease prognosis and treatment that might lighten the burden of chronic kidney disease and also affect on its progression.

  3. Repression of ATMIN in hypoxia is mediated by both p53 (show TP53 Proteins) and HIF-1alpha (show HIF1A Proteins) in an oxygen dependent manner.

  4. ATMIN is required for cell cycle progression and chromosome segregation following replication stress.ATMIN is required for the ATM (show ATM Proteins)-mediated signaling and recruitment of 53BP1 (show TP53BP1 Proteins) to DNA damage sites upon replication stress.

  5. The ASCIZ-DYNLL1 (show DYNLL1 Proteins) feedback loop represents a novel mechanism for auto-regulation of gene expression, where the gene product directly inhibits the transcriptional activator while bound at its own promoter.

  6. these results imply a potential cellular interference between DYNLL1 (show DYNLL1 Proteins) and ATMIN functions.

  7. Asciz (Atmin) deletion or knock-down does not affect ATM levels and activation in mouse, chicken, or human cells

  8. ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein (ASCIZ) required for repair of abasic sites after methylating and oxidative DNA damage but not double-strand breaks. Forms DNA damage-induced foci with RAD51 (show RAD51 Proteins) and ssDNA. ASCIZ foci depend on MLH1 (show MLH1 Proteins).

  9. ATMIN defines a novel NBS1 (show NBN Proteins)-independent pathway of ATM (show ATM Proteins) signalling.

  10. These data suggest that ASCIZ may affect the choice between competing base repair pathways in a manner that reduces the amount of substrates available for Ig gene conversion.

Mouse (Murine) ATM Interactor (ATMIN) interaction partners

  1. oncogenic MYC (show MYC Proteins) expression, which is synthetic lethal with Dynll1 (show DYNLL1 Proteins) deletion in B-2 cells, did not further reduce B-1a cell numbers in Dynll1 (show DYNLL1 Proteins)-defcient mice. we found that the ASCIZ-DYNLL1 (show DYNLL1 Proteins) axis was also required for the early-juvenile development of aggressive MYC (show MYC Proteins)-driven and p53 (show TP53 Proteins)-deficient B cell lymphomas.

  2. ATMIN, therefore, has multiple roles in different cell types, and its absence results in perturbed hematopoiesis, especially during stress conditions and aging.

  3. ASCIZ and its target DYNLL1 (show DYNLL1 Proteins) are essential for the development and expansion of MYC (show MYC Proteins)-driven B cell lymphoma.

  4. These results reveal a new requirement for ATMIN-dependent ATM (show ATM Proteins) signaling in TP53 (show TP53 Proteins)-deficient glioblastoma multiforme, indicating a pro-tumorigenic role for ATM (show ATM Proteins) in the context of these tumors.

  5. findings reveal a novel model for an intestinal bowel disease phenotype that occurs upon combined loss of the DNA repair cofactors ATMIN and NBS1 (show NBN Proteins)

  6. Results show that Atmin is critical for normal kidney development through Wnt (show WNT2 Proteins) signaling pathway modifications.

  7. ATMIN has a role in lung morphogenesis and ciliogenesis through transcriptional regulation

  8. UBR5-mediated ATMIN ubiquitination is a vital event for ATM (show ATM Proteins) pathway selection and activation in response to DNA damage

  9. the antagonism and redundancy of ATMIN and NBS1 (show NBN Proteins) constitute a crucial regulatory mechanism for ATM (show ATM Proteins) signaling and function.

  10. ASCIZ (ATMIN) regulates B cell development by inducing DYNLL1 (LC8 (show DYNLL1 Proteins)) expression which in turn prevents Bim (show BCL2L11 Proteins)-dependent apoptosis in immature B cells in the bone marrow

ATM Interactor (ATMIN) Protein Profile

Protein Summary

Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM.

Gene names and symbols associated with ATM Interactor Proteins (ATMIN)

  • ATM interactor (ATMIN)
  • ATM interactor (atmin)
  • centromere protein N (CENPN)
  • similar to ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein (LOC571606)
  • ATM interactor (Atmin)
  • Asciz protein
  • ATMIN protein
  • mKIAA0431 protein
  • RGD1305781 protein
  • ZNF822 protein

Protein level used designations for ATM Interactor Proteins (ATMIN)

ATM interactor , ATM INteracting protein , ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein , ATM/ATR-substrate CHEK2-interacting zinc finger protein , ATM/ATR-substrate CHK2-interacting zinc finger protein , zinc finger protein 822 , ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein

426138 Gallus gallus
443691 Xenopus laevis
479635 Canis lupus familiaris
571606 Danio rerio
717395 Macaca mulatta
738730 Pan troglodytes
100031731 Monodelphis domestica
100069801 Equus caballus
100356797 Oryctolagus cuniculus
100449573 Pongo abelii
100483255 Ailuropoda melanoleuca
100487308 Xenopus (Silurana) tropicalis
100548302 Meleagris gallopavo
100565641 Anolis carolinensis
100585291 Nomascus leucogenys
23300 Homo sapiens
781217 Bos taurus
234776 Mus musculus
315037 Rattus norvegicus
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