ATP Binding Cassette Transporter A3 (ABCA3) ELISA Kits

The membrane-associated protein encoded by ABCA3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA3 Antibodies (14) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ABCA3 21 Q99758
Anti-Mouse ABCA3 ABCA3 27410 Q8R420
Anti-Rat ABCA3 ABCA3 302973  
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 33 pg/mL 78.12-5000 pg/mL 96 Tests Log in to see 13 to 16 Days

More ELISA Kits for ABCA3 Interaction Partners

Human ATP Binding Cassette Transporter A3 (ABCA3) interaction partners

  1. two ABCA3 mutations (p.R288K and p.R1474W) identified among term and late-preterm infants with respiratory distress syndrome, were characterized.

  2. 1153 patients with diffuse parenchymal lung disease (DPLD (show PLD ELISA Kits)) were registered in the KLR (show KLRK1 ELISA Kits). The DNA of 242 of these patients was sequenced for ABCA3 mutations. 69 patients had at least one variation in the ABCA3 gene. Of 40 patients with two disease-causing ABCA3 mutations, 22 patients were homozygous and 18 heterozygous.

  3. Genes ABCC7 (show CFTR ELISA Kits), A3, A8, A12 (show UGT1A9 ELISA Kits), and C8 prevailed among the most upregulated or downregulated ones. In conclusion, the results supported our theory about general adenosine triphosphate-binding cassette gene expression profiles and their importance for cancer on clinical as well as research levels.

  4. transporter oligomerization is crucial for ABCA3 function.

  5. The TGGAG haplotype may be a risk factor for Respiratory Distress Syndrome in preterm infants in this Chinese population. The haplotype TGGAG was significantly more frequent in RDS (show PRPH2 ELISA Kits) infants than in non-RDS (show PRPH2 ELISA Kits) infants.

  6. Rare mutations in surfactant-associated genes contribute to neonatal respiratory distress syndrome. We resequenced all exons of the ATP-binding cassette member A3 (ABCA3) and we found three ABCA3 mutations in the Han [minor allele frequency (MAF (show MAF ELISA Kits))=0.003] and 7 in the Zhuang (MAF (show MAF ELISA Kits)=0.011) cohorts. The contribution of these rare ABCA3 mutations to disease burden in the south China population is still unknown.

  7. The clinical features of ABCA3 mutations, including onset, severity or clinical course are very heterogeneous. In the two siblings we had a lightly discordant course that could be explained by exposure to different environmental stresses or variable penetrance.

  8. These results provide evidence of ABCA3 as an MLF efflux transporter in human macrophages and support its role in the direct antileishmanial effect of this alkylphosphocholine drug.

  9. Studies indicate that ATP-binding cassette (ABC (show ABCB6 ELISA Kits)), subfamily A (show CYP ELISA Kits), member 3 (ABCA3) is developmentally regulated.

  10. Data discussed the structural features of ABCA3 and how the use of bioinformatics tools could help researchers to obtain a reliable structural model to locate relevant mutations and make genotype/phenotype correlations of affected patients. [review]

Mouse (Murine) ATP Binding Cassette Transporter A3 (ABCA3) interaction partners

  1. Abca3 haploinsufficiency results in an altered biochemical and lung mechanical phenotype, as well as a greater lung injury induced by hyperoxia or mechanical ventilation.

  2. The majority of mice in which Abca3 was deleted in alveolar type II cells died shortly after birth from respiratory distress related to surfactant deficiency.

  3. Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter (show TAP2 ELISA Kits) protein (show LAPTM4A ELISA Kits) ABCA3

  4. showed for the first time expression and subcellular localization of abcb11 (show ABCB11 ELISA Kits) and abca3 in mouse kidney

  5. ABCA3 is necessary for lamellar body biogenesis, surfactant protein-B processing, and lung development late in gestation.

  6. The phenotype of respiratory failure immediately after birth corresponds to the clinical course of severe ABCA3 mutations in human newborns.

  7. Abca3 gene expression is mediated by discrete cis (show CISH ELISA Kits)-acting cassettes that mediate pulmonary cell- and lipid-sensitive pathways regulating surfactant homeostasis.

  8. Iportance of a functional catalytic cycle in lipid transport of ABCA3 suggestsa pathophysiological mechanism of pediatric intterstitial lung disease due to ABCA3 mutation.

ABCA3 Antigen Profile

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death.

Gene names and symbols associated with ABCA3

  • ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 3 (Abca3) antibody
  • ATP-binding cassette, subfamily A (ABC1), member 3 (Abca3) antibody
  • 1810036E22Rik antibody
  • ABC-C antibody
  • Abc3 antibody
  • EST111653 antibody
  • LBM180 antibody
  • SMDP3 antibody

Protein level used designations for ABCA3

ABC transporter 3 , ABC-C transporter , ATP-binding cassette sub-family A member 3 , ATP-binding cassette transporter 3 , ATP-binding cassette, sub-family A (ABC1), member 3

21 Homo sapiens
27410 Mus musculus
302973 Rattus norvegicus
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