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Activin Receptor Type I (ACRV1) ELISA Kits

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Additionally we are shipping Activin Receptor Type I Antibodies (148) and Activin Receptor Type I Proteins (29) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ACRV1 11477 P37172
ACRV1 90 Q04771
ACRV1 79558 P80201
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Top Activin Receptor Type I ELISA Kits at

Showing 9 out of 23 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.063 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 16 to 21 Days
Guinea Pig
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  96 Tests Log in to see 16 to 21 Days
  96 Tests Log in to see 16 to 21 Days

More ELISA Kits for Activin Receptor Type I Interaction Partners

Mouse (Murine) Activin Receptor Type I (ACRV1) interaction partners

  1. Suggest that BMP signaling upregulates the calcineurin (show PPP3CA ELISA Kits)/nuclear factor of activated T cell (show NFATC3 ELISA Kits) pathway via BMP type I receptor ALK2, contributing to cardiac hypertrophy and fibrosis.

  2. results suggest that ACVR1(R206H) causes FOP (show CHTOP ELISA Kits) by gaining responsiveness to the normally antagonistic ligand activin A (show INHBA ELISA Kits), demonstrating that this ligand is necessary and sufficient for driving HO in a genetically accurate model of FOP (show CHTOP ELISA Kits)

  3. The findings suggest that the mutant ALK2 related to Fibrodysplasia ossificans progressiva is enhanced by bone morphogenetic protein type II receptors via the T203-regulated phosphorylation of ALK2.

  4. ACVR1 is required for chondrocyte proliferation and differentiation, particularly in craniofacial and axial elements, but exerts coordinated functions with both BMPR1A (show BMPR1A ELISA Kits) and BMPR1B (show BMPR1B ELISA Kits) throughout the developing endochondral skeleton

  5. expression of constitutively active ALK2 receptor results in significantly increased ASC (show STS ELISA Kits) osteogenic differentiation.

  6. SP-10 is a useful marker for staging the cycle of the seminiferous epithelium. The anti-SP-10 antibody works well in different fixatives, on paraffin-embedded as well as cryosections

  7. Data indicate that activin A receptor type 1 (Alk2) is a direct regulator of cartilage formation and mediates chondrogenic commitment of progenitor cells.

  8. Tmem176b (show TMEM176B ELISA Kits) mRNA levels were upregulated by stable transfection of ALK2 (R206H) in mouse myoblastic C2C12 cells.

  9. AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.

  10. Our work clarifies the conserved mechanisms through which BMPs regulate peri (show POSTN ELISA Kits)-implantation in rodents and primates and, for the first time, uncovers a linear pathway of BMP signaling through ALK2 to regulate CEBPB (show CEBPB ELISA Kits)

Human Activin Receptor Type I (ACRV1) interaction partners

  1. Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.

  2. The higher PE activin A (show INHBA ELISA Kits) concentrations resulted in abnormal endothelial functions, which may contribute to the systemic maternal vascular endothelial cell dysfunction observed in the disorder.

  3. A report of two patients has been presented with multi-system involvement in a severe variant of fibrodysplasia ossificans progressiva caused by the ACVR1 c.772G>A; R258G mutation.

  4. Fibrodysplasia ossificans progressiva-ACVR1 abnormally transduces bone morphogenetic protein signaling in response to Activin-A (show INHBA ELISA Kits).

  5. Changes in the binding site residue(e.g. pre-hinge region in ALK2) or side chain orientation (e.g. Tyr219 in caALK2 vs. wtALK2), or ligand modification (e.g. DMH1 vs. LDN193189) causes distinct binding profiles and selectivity among BMP inhibitors.

  6. heterozygous mutation i.e., c.617(G>A)in ACVR1 was detected in patients with rare genetic disorder - Fibrodysplasia ossificans progressiva

  7. miR (show MLXIP ELISA Kits)-148a is an important mediator of ACVR1, thus offering a new potential target for the development of therapeutic agents against Fibrodysplasia ossificans progressiva.

  8. Genetic analysis of ACVR1 identified the recurrent allelic variant c.617 G>A; p.R206H in 12 of 14 Fibrodysplasia Ossificans Progressiva (FOP)patients. One of the remaining patients had a previously reported allele c.1067G>A; p.G356D in the 9th exon and the second allele c.983G>A; p.G328E in the 8th exon of ACVR1.

  9. clinically aggressive stem cell-like subtype of hepatocellular carcinoma characterized by miR (show MLXIP ELISA Kits)-148a-ACVR1-BMP-Wnt (show WNT2 ELISA Kits) circuit

  10. compounds demonstrated consistent binding to a panel of mutant and wild-type ALK2 proteins

Activin Receptor Type I (ACRV1) Antigen Profile

Antigen Summary

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Gene names and symbols associated with ACRV1

  • activin A receptor, type 1 (Acvr1) antibody
  • activin A receptor, type I (ACVR1) antibody
  • activin A receptor, type I (Acvr1) antibody
  • ActR-I antibody
  • ActR-IA antibody
  • ACTRI antibody
  • ActRIA antibody
  • Acvr antibody
  • ACVR1A antibody
  • ACVRLK2 antibody
  • Alk-2 antibody
  • ALK2 antibody
  • Alk8 antibody
  • D330013D15Rik antibody
  • FOP antibody
  • SKR1 antibody
  • Tsk7L antibody
  • TSRI antibody

Protein level used designations for ACRV1

TGF-B superfamily receptor type I , TSK-7L , TSR-I , activin receptor type I , activin receptor type-1 , serine/threonine-protein kinase receptor R1 , activin A receptor, type II-like kinase 2 , activin receptor-like kinase 2 , hydroxyalkyl-protein kinase , ACTR-I , SKR1 , activin A receptor, type 1 , activin type I receptor , type I TGF B receptor , activin A receptor, type I , activin receptor type IA

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