Activin Receptor Type I (ACRV1) ELISA Kits

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Additionally we are shipping Activin Receptor Type I Antibodies (164) and Activin Receptor Type I Proteins (33) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ACRV1 11477 P37172
ACRV1 90 Q04771
ACRV1 79558 P80201
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Top Activin Receptor Type I ELISA Kits at

Showing 10 out of 15 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
Monkey 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
Mouse 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
Rat 0.1 ng/mL 250-5000 pg/mL   96 Tests Log in to see 15 to 18 Days
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 15 to 18 Days

More ELISA Kits for Activin Receptor Type I Interaction Partners

Mouse (Murine) Activin Receptor Type I (ACRV1) interaction partners

  1. The authors demonstrated that ubiquitin-specific protease (USP) 4 (show USP4 ELISA Kits) strongly induces activin (show Actbeta ELISA Kits)/BMP signaling by removing the inhibitory monoubiquitination from SMAD4 (show SMAD4 ELISA Kits).

  2. Enhanced SMAD (show SMAD1 ELISA Kits)-dependent BMP signaling through constitutively active ACVR1 in palatal epithelium causes submucous cleft palate in mice, via medial-edge-epithelium persistence presumably due to the up regulation of DeltaNp63 andresultingreductionofcaspase-3 activation. 2.

  3. BMP signaling mediated by coordination of ALK2/ACVR1, ALK3/BMPR1A (show BMPR1A ELISA Kits), and BMPR2 (show BMPR2 ELISA Kits) is an essential proangiogenic cue for retinal vessels.

  4. This study showed that Gja1 (show GJA1 ELISA Kits) may act downstream of cAMP-PKA signal to mediate the effects of Acvr1 on the differentiation of uterine stromal cells through targeting Hand2 (show HAND2 ELISA Kits).

  5. Results showed activin (show Actbeta ELISA Kits)-C and follistatin (show FST ELISA Kits) are differentially expressed during prostate development and suggested that the antagonistic property of follistatin (show FST ELISA Kits) is secondary to the action of activin (show Actbeta ELISA Kits)-C. Study provides evidence to support a role of activin (show Actbeta ELISA Kits)-C in prostate development and provides new insights in the spatiotemporal localization of activins and their antagonists during mouse prostate development.

  6. BMPR1B plays distinct roles from BMPR1A and ACVR1 in maintaining bone mass and transducing BMP signaling

  7. Suggest that BMP signaling upregulates the calcineurin (show PPP3CA ELISA Kits)/nuclear factor of activated T cell (show NFATC3 ELISA Kits) pathway via BMP type I receptor ALK2, contributing to cardiac hypertrophy and fibrosis.

  8. results suggest that ACVR1(R206H) causes FOP (show CHTOP ELISA Kits) by gaining responsiveness to the normally antagonistic ligand activin A (show INHBA ELISA Kits), demonstrating that this ligand is necessary and sufficient for driving HO in a genetically accurate model of FOP (show CHTOP ELISA Kits)

  9. The findings suggest that the mutant ALK2 related to Fibrodysplasia ossificans progressiva is enhanced by bone morphogenetic protein type II receptors via the T203-regulated phosphorylation of ALK2.

  10. ACVR1 is required for chondrocyte proliferation and differentiation, particularly in craniofacial and axial elements, but exerts coordinated functions with both BMPR1A (show BMPR1A ELISA Kits) and BMPR1B (show BMPR1B ELISA Kits) throughout the developing endochondral skeleton

Human Activin Receptor Type I (ACRV1) interaction partners

  1. The effects of ACVR1/ALK2 mutations causing fibrodysplasia ossificans progressiva are extended to the central nervous system. Brainstem hamartomatous lesions and dysmorphisms, variably associated with dentate nucleus and basal ganglia signal abnormalities and/or calcifications, may represent useful disease hallmarks.

  2. Low ALK2 expression is associated with invasiveness of breast cancer.

  3. Further investigation on clinical ESCC samples and non-tumorous adjacent tissue found that tumors with triple-positive BMP6 (show BMP6 ELISA Kits), ALK2 and BMPRII (show BMPR2 ELISA Kits) had deeper growth than tumors with only BMP6 (show BMP6 ELISA Kits) expression

  4. The clinical manifestations, the disease course, and the molecular findings of involvement of ACVR1 gene in this family are suggestive of "FOP variant" or an unusual ACVR1-related skeletal dysplasia

  5. Activin-A (show INHBA ELISA Kits) is increased in the airway of asthmatics and peaks during asthma exacerbations.Activin-A signalling pathways are dysregulated in severe asthma.

  6. Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.

  7. The higher PE activin A (show INHBA ELISA Kits) concentrations resulted in abnormal endothelial functions, which may contribute to the systemic maternal vascular endothelial cell dysfunction observed in the disorder.

  8. A report of two patients has been presented with multi-system involvement in a severe variant of fibrodysplasia ossificans progressiva caused by the ACVR1 c.772G>A; R258G mutation.

  9. Fibrodysplasia ossificans progressiva-ACVR1 abnormally transduces bone morphogenetic protein signaling in response to Activin-A (show INHBA ELISA Kits).

  10. Changes in the binding site residue(e.g. pre-hinge region in ALK2) or side chain orientation (e.g. Tyr219 in caALK2 vs. wtALK2), or ligand modification (e.g. DMH1 vs. LDN193189) causes distinct binding profiles and selectivity among BMP inhibitors.

Activin Receptor Type I (ACRV1) Antigen Profile

Antigen Summary

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Gene names and symbols associated with ACRV1

  • activin A receptor, type 1 (Acvr1) antibody
  • activin A receptor, type I (ACVR1) antibody
  • activin A receptor, type I (Acvr1) antibody
  • ActR-I antibody
  • ActR-IA antibody
  • ACTRI antibody
  • ActRIA antibody
  • Acvr antibody
  • ACVR1A antibody
  • ACVRLK2 antibody
  • Alk-2 antibody
  • ALK2 antibody
  • Alk8 antibody
  • D330013D15Rik antibody
  • FOP antibody
  • SKR1 antibody
  • Tsk7L antibody
  • TSRI antibody

Protein level used designations for ACRV1

TGF-B superfamily receptor type I , TSK-7L , TSR-I , activin receptor type I , activin receptor type-1 , serine/threonine-protein kinase receptor R1 , activin A receptor, type II-like kinase 2 , activin receptor-like kinase 2 , hydroxyalkyl-protein kinase , ACTR-I , SKR1 , activin A receptor, type 1 , activin type I receptor , type I TGF B receptor , activin A receptor, type I , activin receptor type IA

11477 Mus musculus
90 Homo sapiens
478757 Canis lupus familiaris
338068 Bos taurus
79558 Rattus norvegicus
395246 Gallus gallus
443161 Ovis aries
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