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Necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. Additionally we are shipping AP1AR Kits (4) and and many more products for this protein.
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Human Polyclonal AP1AR Primary Antibody for ICC, IF - ABIN4280871
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
conclude that a specific fraction of the AP2 (show GTF3A Antibodies)-derived endocytic pathway is dedicated to secretory purposes under the control of AP1 (show FOSB Antibodies) and Gadkin
Studies unravel the molecular basis for Gadkin-mediated AP-1 (show FOSB Antibodies) recruitment to TGN (show TG Antibodies)/endosomal membranes and identify a novel subtype of the AP-1 (show FOSB Antibodies)-binding motif.
Gadkin (gamma-BAR), a peripheral membrane protein localized to the trans-Golgi network and to endosomal vesicles, directly associates with the clathrin adaptor AP-1 (show FOSB Antibodies) and the motor protein kinesin KIF5 (show KIF5A Antibodies), potentially regulating endosomal vesicle dynamics.
Necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1- adaptin attenuates the release of the AP-1 complex from membranes.
AP-1 complex-associated regulatory protein
, adapter-related protein complex 1-associated regulatory protein
, gamma-1-adaptin brefeldin A resistance protein
, gamma1-adaptin brefeldin A resistance protein, gamma-BAR