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Adrenergic, beta-2-, Receptor, Surface Proteins (ADRB2)

ADRB2 encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. Additionally we are shipping beta 2 Adrenergic Receptor Antibodies (249) and beta 2 Adrenergic Receptor Kits (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADRB2 11555 P18762
ADRB2 154 P07550
Rat ADRB2 ADRB2 24176  
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Top beta 2 Adrenergic Receptor Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.25 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days

ADRB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Adrenergic, beta-2-, Receptor, Surface (ADRB2) Interaction Partners

Zebrafish Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

  1. Zebrafish larvae lacking beta1AR (show ADRB1 Proteins) expression by morpholino knockdown displayed lower heart rates than control fish, whereas larvae deficient in both beta2aAR and beta2bAR expression exhibited significantly higher heart rates than controls.

Mouse (Murine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

  1. Housing temperature-induced stress drives therapeutic resistance in murine tumor models through beta2-adrenergic receptor activation.

  2. Quantification of beta adrenergic receptor subtypes in beta-arrestin knockout mouse airways.

  3. our results demonstrate that the beta2-adrenergic receptor is a key regulator of hepatic autophagy, and that the beta-blocker propranolol can independently induce a late block in autophagy.

  4. promotes the M2 macrophage phenotype in mouse models of endotoxemia and LPS (show TLR4 Proteins)-induced acute lung injury

  5. This study demonstrated that TNFalpha (show TNF Proteins) plays a role in insulin (show INS Proteins) resistance in beta2KO mice.

  6. beta2AR-mediated signals inhibited lymph node egress of antigen-primed T cells and reduced their recruitment into peripheral tissues.

  7. role of beta-ARs (show SLURP1 Proteins) in early muscle regeneration

  8. Gene therapy or pharmacological means of increasing Galphas (show GNAS Proteins) (or its coupling efficiency to beta2AR) thus represent an interface for development of novel therapeutic agents for improvement of beta-agonist therapy.

  9. These data indicate that increased insulin receptor (show INSR Proteins) signaling, may directly impair beta2-adrenergic receptor regulated cardiac contractility.

  10. specific interactions between the ligand and the Tyr (show TYR Proteins)-308 residue of beta2-AR stabilize receptor conformations favoring the receptor-Gs protein coupling and subsequently result in Gs-biased agonism.

Cow (Bovine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

  1. These results indicate dependence of hepatic glucocorticoid and adrenergic receptors on stage of maturation in neonatal calves and emphasize the association of alpha1-adrenergic receptor and glucocorticoid receptor (show NR3C1 Proteins) with neonatal glucose and lipid metabolism.

  2. ADRb2 shows lipid scrambling activity.

  3. relationship between luteal concentrations of oxytocin (OT), noradrenaline (NA), progesterone (P4), oxytocin receptors (OT-R (show OXTR Proteins)) and beta(2)-adrenoreceptors (beta(2)-R) gene expression and their protein level throughout the estrous cycle

Human Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

  1. Results revealed a new disruptive variant in ADRB2 gene coding for a protein implicated in signal transduction and energy metabolism in the heart.

  2. REVIEW: recent advances in experimental techniques applied in the study of functionally selective GPCR conformations and breakthrough data obtained in these studies particularly those of the beta2-adrenoceptor

  3. Suggest a common regulatory pattern for the beta(2)-AR/GRK2 (show ADRBK1 Proteins) which is independent of cellular type or pathology.

  4. Suggest that the ADRB2 Gly16Arg polymorphism is predictive of perioperative vasopressor requirements in patients anesthetized for elective neurosurgery.

  5. there was a significant LST (show ALX4 Proteins) gain with exercise on the B2Glu27+ background compared to loss among controls and no intervention effect on the B2Glu27- background.

  6. In a South Indian population, ADRB2 Arg/Gly may not form a susceptible variant to develop asthma and is not a standard predictive marker to bronchodilator response; nevertheless, the patterns in asthma severity can be predicted by analyzing this variant.

  7. functional evidence that G-protein coupling to the beta2AR stabilizes a 'closed' receptor conformation characterized by restricted access to and egress from the hormone-binding site

  8. None of the four polymorphisms in ADRB2 gene were associated with a risk of asthma in a current children population

  9. beta2-adrenergic receptor signaling promotes pancreatic ductal adenocarcinoma progression by facilitating PCBP2 (show PCBP2 Proteins)-dependent c-myc (show MYC Proteins) expression.

  10. Our data suggest that b2-AR may be a new useful biomarker for predicting prognosis in Her2 (show ERBB2 Proteins)-positive breast cancer and may also be a promising selective therapeutic target for the aggressive subtype of breast cancer.

Pig (Porcine) Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

  1. A persistent B2R (show BDKRB2 Proteins)-beta2AR heterodimer was confirmed in bradykinin-stimulated and non-stimulated left ventricular myocardium. BK transactivation of beta2AR enhanced beta2AR-mediated release of tPA (show PLAT Proteins).

  2. Prolactin (show PRL Proteins) infusion brought about the inhibition of a vasodilatory beta(2)-adrenergic receptor-mediated effect related to the NO intracellular pathway

  3. Intracoronary intermedin (show ADM2 Proteins) 1-47 augments cardiac perfusion and function in anesthetized pigs: role of calcitonin (show CALCA Proteins) receptors and beta-adrenoreceptor-mediated nitric oxide release.

Rhesus Monkey Adrenergic, beta-2-, Receptor, Surface (ADRB2) interaction partners

  1. The results imply ADRB-2-mediated actions in the development of primate follicles

beta 2 Adrenergic Receptor (ADRB2) Protein Profile

Protein Summary

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Gene names and symbols associated with ADRB2

  • adrenoceptor beta 2, surface (ADRB2)
  • adrenergic receptor, beta 2b (adrb2b)
  • beta2-adrenergic receptor (LOC100136153)
  • adrenergic receptor, beta 2 (Adrb2)
  • adrenergic, beta-2-, receptor, surface (ADRB2)
  • adrenoceptor beta 2, surface (Adrb2)
  • Adrb-2 protein
  • adrb2 protein
  • ADRB2R protein
  • ADRBR protein
  • B2AR protein
  • Badm protein
  • BAR protein
  • BETA2AR protein
  • Gpcr7 protein
  • zgc:162188 protein

Protein level used designations for ADRB2

adrenergic receptor beta-2 , adrenergic, beta-2-, receptor, surface , beta-2 adrenergic receptor , beta-2b-adrenergic receptor , beta-2 adrenoceptor , beta-2 adrenoreceptor , beta 2-AR , adrenergic receptor beta 2 , adrenergic, beta-2, receptor, surface , catecholamine receptor , beta2-adrenergic receptor , Adrenergic beta 2- receptor surface , adrenergic receptor, beta 2 , Beta-2 adrenergic receptor , Beta-2 adrenoceptor , Beta-2 adrenoreceptor , beta 2 adrenergic receptor , beta-2-adrenergic receptor

100170320 Ovis aries
100060659 Equus caballus
100037315 Danio rerio
100136153 Oncorhynchus mykiss
11555 Mus musculus
281605 Bos taurus
154 Homo sapiens
403910 Canis lupus familiaris
24176 Rattus norvegicus
493767 Felis catus
100722663 Cavia porcellus
397357 Sus scrofa
471690 Pan troglodytes
101836719 Mesocricetus auratus
710146 Macaca mulatta
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