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ARMS2 encodes a protein that is thought to play a role in diseases in the elderly. Additionally we are shipping ARMS2 Antibodies (20) and ARMS2 Kits (1) and many more products for this protein.
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OCT (show Plxna2 Proteins) scans revealed lower retinal thickness in patients homozygous for CFH (show CFH Proteins) or ARMS2, which was caused by a significantly reduced photoreceptor layer. The number and ultrastructure of drusen were also significantly different.
This study suggests that in familial age-related macular degeneration patients, the common genetic risk variant in ARMS2 is less important compared to sporadic age-related macular degeneration.
this work we show that ARMS2 is externalized via an unconventional pathway bypassing Golgi.
Interaction effects between supplement groups and individual complement factor H (CFH (show CFH Proteins)) Y402H and age-related maculopathy susceptibility 2 (ARMS2) genotypes, and composite genetic risk groups combining the number of risk alleles for both loci, were evaluated for their association with progression
EMD (show EMD Proteins) were not AMD (show AMD1 Proteins)-independently associated with CFH (show CFH Proteins) or ARMS2 genotypes. Our results indicate that patients without AMD (show AMD1 Proteins) but with EMD (show EMD Proteins) can serve as controls in studies evaluating AMD (show AMD1 Proteins) risk factors.
Variants in ARMS2 carry risk of age-related macular degeneration.
CFH (show CFH Proteins), ARMS2, and C3 were associated with specific features of neovascularization at the time patients were enrolled in Comparison of Age-Related Macular Degeneration Treatments Trials .
Subfoveal choroidal thickness and choroidal vascular hyperpermeability in eyes with treatment-naive polypoidal choroidal vasculopathy were associated with ARMS2 A69S (rs10490924) and CFH (show CFH Proteins) (rs1329428).
Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1 (show PLEKHA1 Proteins), ARMS2, and HTRA1 (show HTRA1 Proteins) with high linkage disequilibrium.
No significant interaction was found between DHA supplementation benefit and ARMS2 A69S SNP.
This gene encodes a protein that is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration.
age-related maculopathy susceptibility protein 2
, age-related maculopathy susceptibility 2