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Aldo-keto Reductase Family 1, Member C2 (AKR1C2) ELISA Kits

AKR1C2 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. Additionally we are shipping AKR1C2 Antibodies (70) and AKR1C2 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
AKR1C2 1646 P52895
Anti-Rat AKR1C2 AKR1C2 291283 Q6AYQ2
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Top AKR1C2 ELISA Kits at

Showing 1 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.061 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days

Top referenced AKR1C2 ELISA Kits

  1. Human AKR1C2 ELISA Kit for Sandwich ELISA - ABIN1117945 : Kuang, Zhou, Li, Ren, Li, Wang, Li, Tang, Zhang, Zhao: Proteomics-based identification of secreted protein dihydrodiol dehydrogenase 2 as a potential biomarker for predicting cisplatin efficacy in advanced NSCLC patients. in Lung cancer (Amsterdam, Netherlands) 2012 (PubMed)
    Show all 2 references for ABIN1117945

More ELISA Kits for AKR1C2 Interaction Partners

Human Aldo-keto Reductase Family 1, Member C2 (AKR1C2) interaction partners

  1. We identified two powerful genes in the liver cancer metastasis process, AEG-1 (show MTDH ELISA Kits) and AKR1C2.

  2. Identify two novel factors, AKR1C2 (positive factor) and NF1 (show NF1 ELISA Kits) (negative factor), as the AEG-1 (show MTDH ELISA Kits) downstream players in the process of metastasis in liver cancer.

  3. The endogenous HMOX1 (show HMOX1 ELISA Kits) gene but not the AKR1C2 gene is strongly repressed by Bach1 (show BACH1 ELISA Kits) in HaCaT keratinocytes.

  4. In model cell lines of endometrial cancer, AKR1C2 and SRD5A1 (show SRD5A1 ELISA Kits) have crucial roles in progesterone metabolism.

  5. Significantly higher levels of SRD5A1 (show SRD5A1 ELISA Kits), AKR1C2, AKR1C3 (show AKR1C3 ELISA Kits), and HSD17B10 (show HSD17B10 ELISA Kits) mRNA were however found in bone metastases than in non-malignant and/or malignant prostate tissue

  6. The V54L mutation significantly decreases the 3alpha-hydroxysteroid dehydrogenase activity of DDH2 for the reduction of dihydrotestosterone.

  7. DDH2 expression might be a potential predictor and monitor of cisplatin efficacy in advanced NSCLC patients.

  8. Data suggest that interleukin-1beta facilitates progesterone metabolism in cervical fibroblasts by regulating expression of AKR1C1 (show DDH ELISA Kits) and AKR1C2.

  9. Data suggest that modulation of AKR1C2 by glucocorticoids (dexamethasone in this study) locally modifies exposure of adipose cells to endogenous androgens; thus, AKR1C2 activation/inactivation may be involved in regional fat deposition.

  10. role of AKR1C2 in the metabolism of testosterone and progesterone via the 5beta-reductase pathway.

AKR1C2 Antigen Profile

Antigen Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with AKR1C2

  • aldo-keto reductase family 1, member C2 (AKR1C2) antibody
  • aldo-keto reductase family 1, member C2 (Akr1c2) antibody
  • AKR1C-pseudo antibody
  • Akr1c21 antibody
  • BABP antibody
  • DD antibody
  • DD2 antibody
  • DDH2 antibody
  • HAKRD antibody
  • HBAB antibody
  • MCDR2 antibody
  • SRXY8 antibody

Protein level used designations for AKR1C2

3-alpha-HSD3 , DD-2 , DD/BABP , aldo-keto reductase family 1 member C2 , chlordecone reductase homolog HAKRD , dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III , pseudo-chlordecone reductase , trans-1,2-dihydrobenzene-1,2-diol dehydrogenase , type II dihydrodiol dehydrogenase , 17-alpha-HSD , 17-alpha-hydroxysteroid dehydrogenase , 3(or 17)-alpha-hydroxysteroid dehydrogenase , 3-alpha-hydroxysteroid dehydrogenase , aldo-keto reductase family 1 member C21 , aldo-keto reductase family 1, member C21

1646 Homo sapiens
291283 Rattus norvegicus
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