Ameloblastin (Enamel Matrix Protein) Proteins (AMBN)

AMBN encodes the nonamelogenin enamel matrix protein ameloblastin. Additionally we are shipping AMBN Antibodies (10) and AMBN Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AMBN 11698 O55189
Rat AMBN AMBN 25376 Q62840
AMBN 258 Q9NP70
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Top AMBN Proteins at

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Wheat germ Human GST tag   10 μg Log in to see 11 to 12 Days
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days

AMBN Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,

Top referenced AMBN Proteins

  1. Human AMBN Protein expressed in Wheat germ - ABIN1344966 : Geng, White, Paine, Snead: Protein Interaction between Ameloblastin and Proteasome Subunit ? Type 3 Can Facilitate Redistribution of Ameloblastin Domains within Forming Enamel. in The Journal of biological chemistry 2015 (PubMed)

More Proteins for Ameloblastin (Enamel Matrix Protein) (AMBN) Interaction Partners

Mouse (Murine) Ameloblastin (Enamel Matrix Protein) (AMBN) interaction partners

  1. Protein interaction between Ambn and Psma3 (show PSMA3 Proteins) can facilitate redistribution of ameloblastin domains within forming enamel.

  2. AMBN may function as a growth factor-like molecule solubilized in the aqueous microenvironment. In jaws (show IMPAD1 Proteins), it might play a role in bone physiology through autocrine/paracrine pathways, particularly during development and stress-induced remodeling.

  3. Ameloblastin (AMBN) expression may be regulated in a site-specific manner and identify AMBN as a putative in vivo marker of the site-specific fingerprint of bone organs

  4. Ambn plays a crucial role in the regulation of cranial bone growth and suture closure via Msx 2 suppression and proliferation inhibition.

  5. Blocking integrin alpha2beta1 and ERK 1 (show MAPK3 Proteins)/2 pathways alleviated the effects of AMBN on osteoclast differentiation.

  6. ERP (show PDIA3 Proteins) expression follows defined developmental profiles; affects osteoblast differentiation, mineralization, calvarial bone development. with role in developing enamel matrix, ERPs retain conserved function related to bone biomineralization.

  7. AMBN may regulate differentiation state of Hertwig's epithelial root sheath-derived cells and its expression fuctions as a trigger for normal root formation.

  8. All lines expressing detectable levels of ameloblastin at least partially recovered the enamel phenotype. Ameloblastin is essential for dental enamel formation.

  9. study may implicate the role of the ameloblastin gene locus in the etiology of a number of undiagnosed autosomally dominant cases of amelogenesis imperfecta

  10. Ameloblastin is a cell adhesion molecule (show MCAM Proteins) essential for amelogenesis, and it plays a role in maintaining the differentiation state of secretory stage ameloblasts by binding to ameloblasts and inhibiting proliferation.

Human Ameloblastin (Enamel Matrix Protein) (AMBN) interaction partners

  1. Association between caries experience (caries-free versus caries affected) depending on asthma status and SNPs was tested. Logistic regression showed an association between AMBN rs4694075 and caries experience. Ameloblastin is associated w/caries in asthmatic children.

  2. Protein interaction between Ambn and Psma3 (show PSMA3 Proteins) can facilitate redistribution of ameloblastin domains within forming enamel.

  3. Authors perform an evolutionary analysis of mammalian AMBN sequences in order to predict functionally important sites of the protein and to identify candidate disease-associated mutations responsible for the protein function and identify AMBN as a candidate for amelogenesis imperfect in humans.

  4. Report shows for the first time that AMBN mutations cause non-syndromic human amelogenesis imperfecta and confirms that mouse models with disrupted Ambn function are valid.

  5. two genetic variants (rs2337359 upstream of TUFT1 (show TUFT1 Proteins) and missense rs7439186 in AMBN) involved in gene-by-fluoride interactions.

  6. We found a trend for association between variation in AMBN and MIH in both cohorts, which may suggest that variation in the regulation of AMBN is a mechanism that leads to MIH.

  7. AMBN ribbons exhibited lengths ranging from tens to hundreds of nm. Deletion analysis and NMR spectroscopy revealed that N-terminal segment encoded by exon 5 comprises two short independently structured regions and plays a role in self-assembly of AMBN

  8. AMBN does not influence osteogenic activity in vitro under the conditions used

  9. ameloblastin is expressed in osteoblasts and functions as a promoting factor for osteogenic differentiation via a novel pathway through the interaction between CD63 (show CD63 Proteins) and integrin beta1

  10. found to induce, directly and indirectly, signal transducer and activator of transcription (STAT) 1 (show STAT1 Proteins) and 2 and downstream factors in the interferon (show IFNA Proteins) pathway

AMBN Protein Profile

Protein Summary

This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect.

Gene names and symbols associated with AMBN

  • ameloblastin (Ambn)
  • ameloblastin (enamel matrix protein) (AMBN)

Protein level used designations for AMBN

amelin , ameloblastin , ameloblastin, enamel matrix protein , sheathlin

11698 Mus musculus
25376 Rattus norvegicus
258 Homo sapiens
280995 Bos taurus
397102 Sus scrofa
482185 Canis lupus familiaris
Selected quality suppliers for AMBN Proteins (AMBN)
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