Apolipoprotein L, 1 Proteins (APOL1)

APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Additionally we are shipping APOL1 Antibodies (119) and APOL1 Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOL1 8542 O14791
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Top APOL1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human GST tag,S tag,His tag   100 μg Log in to see 15 to 18 Days
$672.00
Details

APOL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,

More Proteins for Apolipoprotein L, 1 (APOL1) Interaction Partners

Zebrafish Apolipoprotein L, 1 (APOL1) interaction partners

  1. zApoL1 is essential for proper blood filtration in the zebrafish glomerulus and that zApoL1 affects the expression of nephrin (show NPHS1 Proteins)

Human Apolipoprotein L, 1 (APOL1) interaction partners

  1. Two APOL1 renal-risk variants are associated with longer dialysis survival in African Americans with non-diabetic end-stage renal disease.

  2. The frequency of APOL1 risk variants ranged from 7.0% to 11.0%.

  3. The synergy of circulating factor suPAR and APOL1 G1 or G2 on alphavbeta3 integrin activation is a mechanism for CKD.

  4. Among African Americans with hypertension-attributed chronic kidney disease, APOL1 risk variants were not associated with an overall risk for cardiovascular disease although some signals for cardiovascular mortality were noted.

  5. The proteomic profile of apoL1 is modified in HDLs (show CSF1R Proteins) of high cardiovascular risk patients, and apoL1 plasma levels are significantly lower in serum and in HDL3 of patients that will suffer an adverse cardiac event within 3 years.

  6. Relationships between APOL1 kidney risk variants and cardiovascular disease (CVD) susceptibility and CVD-related death remain controversial. Some studies detected an increased risk for CVD, whereas others support protection from death and subclinical CVD and cerebrovascular disease

  7. mice with podocyte-specific expression of either APOL1 risk allele (G1 or G2), but not of the G0 allele, develop functional (albuminuria and azotemia), structural (foot-process effacement and glomerulosclerosis) and molecular (gene-expression) changes that closely resemble human kidney disease. Expression of the risk-variant APOL1 alleles interferes with endosomal trafficking and blocks autophagic flux.

  8. APOL1 single nucleotide polymorphisms are associated with nephropathy.

  9. We report an unadjusted incidence of 1.2 CKD cases/100 person-years (95% CI: 0.5 to 2.5) in PHIV youth carrying APOL1 high-risk genotypes, with important implications for sub-Saharan Africa

  10. Overall, our results suggest podocyte depletion could predispose individuals with APOL1 risk genotypes to kidney disease in response to a second stressor, and add to other published evidence associating APOL1 expression with preeclampsia

APOL1 Protein Profile

Protein Summary

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Apolipoprotein L, 1 Proteins (APOL1)

  • apolipoprotein L, 1 (apol1)
  • apolipoprotein L, 1 (APOL1)
  • APO-L protein
  • APOL protein
  • APOL-I protein
  • FSGS4 protein
  • si:rp71-1g18.12 protein
  • wu:fa95b12 protein
  • wu:fc30h04 protein

Protein level used designations for Apolipoprotein L, 1 Proteins (APOL1)

apolipoprotein L1

GENE ID SPECIES
560340 Danio rerio
8542 Homo sapiens
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