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BCL2-Associated Athanogene 1 Proteins (BAG1)

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death.

list all proteins Gene Name GeneID UniProt
Mouse BAG1 BAG1 12017 Q60739
BAG1 573 Q99933
BAG1 297994 B0K019
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Top BAG1 Proteins at

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Rat T7 tag,His tag 100 μg Log in to see 11 to 13 Days
Human Un-conjugated 5 μg Log in to see 6 Days

BAG1 Proteins by Origin and Source

Origin Expressed in Conjugate

Rat (Rattus)

More Proteins for BCL2-Associated Athanogene 1 (BAG1) Interaction Partners

Mouse (Murine) BCL2-Associated Athanogene 1 (BAG1) interaction partners

  1. The BAG-1 stabilizes F508del-CFTR by direct binding, probably competing out ubiquitin to partially avoid its proteasomal degradation.

  2. The membrane form of heparin binding EGF-like growth factor (show HBEGF Proteins) (ProHB-EGF (show EGF Proteins)) is most likely able to trigger the nuclear translocation of BAG-1 in keeping its level high.

  3. Hemoxygenase (show HMOX1 Proteins) 1 deficiency provoked diminished Bag-1 level upon LPS (show TLR4 Proteins) treatment

  4. this study first reported the solution structure of mBAG-1 (show LRRC4 Proteins)-UBH and the growth factor precursor-interacting motif on the protein.

  5. Bag-1 proteins function as regulators of the action of selective transcription factors.

  6. during development of mouse autopods, BAG-1 expression is downregulated upon the initiation of interdigital apoptosis (BAG-1)

  7. Bag1 is a regulator and marker of neuronal differentiation

  8. BAG1 displays potent neuroprotective activity in vivo against stroke.

  9. Since, BAG-1 is essential for cell survival, its association with tNhtt aggregates might disrupt its normal function and thereby promote polyglutamine-expanded tNhtt-induced cell death.

  10. Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells.

Human BCL2-Associated Athanogene 1 (BAG1) interaction partners

  1. Taken together, these data indicate that Bag-1 up-regulation is required to maintain apoptosis resistance in human cytomegalovirus-infected cells.

  2. the combined effects of BAG-1 and XPD (show ERCC2 Proteins) polymorphisms on chemotherapy sensitivity and survival in patients with advanced non-small-cell lung cancer, which might be the important predictive markers for platinum-based chemotherapy efficacy.

  3. Bag-1 indirectly affects cell survival through c-Myc (show MYC Proteins) activated signalling that causes elevation of ornithine decarboxylase (show ODC1 Proteins) levels, leading to an increase of the polyamine content.

  4. Overexpression of miR (show MLXIP Proteins)-138 inhibited cell proliferation by directly suppressing the expression of Bag-1.

  5. The expression of BAG-1 was upregulated in chronic non-eosinophilic rhinosinusitis.

  6. BAG-1 expression was high in esophageal carcinoma tissues compared to normal esophagus. After Eca109 cells were transfected with BAG-1-siRNA, the proliferation and invasive capabilities of the cells were decreased while the apoptosis rate was enhanced.

  7. BAG-1M mediates Hsp70 (show HSP70 Proteins) inhibition downstream of NF-kappaB (show NFKB1 Proteins).

  8. distinct isoforms of BAG-1 had different anti-apoptotic ability in breast cancer cells treated with the 4-OH TAM (show CCNA1 Proteins).

  9. BAG-1M and HspBP1 (show HSPBP1 Proteins) had differential impacts on the dynamic composition of steroid receptor (show ESR2 Proteins) folding complexes

  10. The results present that the constructed shRNA plasmids significantly inhibited the expression of mRNA and protein of Lo Vo cell BAG-1, and can maintain the effect for a long term

BAG1 Protein Profile

Protein Summary

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Gene names and symbols associated with BAG1

  • BCL2-associated athanogene 1 (Bag1)
  • BCL2-associated athanogene (BAG1)
  • BCL2-associated athanogene (Bag1)
  • Bag-1 protein
  • HAP protein
  • RAP46 protein

Protein level used designations for BAG1

BAG family molecular chaperone regulator 1 , Bcl-2-binding protein , bcl-2-associated athanogene 1 , Bcl-2 associating athanogene-1 protein , glucocortoid receptor-associated protein RAP46 , receptor-associated protein, 46-KD

12017 Mus musculus
573 Homo sapiens
297994 Rattus norvegicus
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